Genetic Counselling, Testing, and Management of Hereditary Breast and Ovarian Cancer Syndrome in India: Updated Expert Consensus Recommendations from Indian Society of Medical and Pediatric Oncology
Introduction Hereditary breast and ovarian cancer (HBOC) is driven by mutations in BRCA1/2 and related genes. Their understanding is vital to appropriate management of such patients and at-risk families, including counselling and genetic testing. Several important recent advances have mad...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2025-06-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788727 |
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| author | Hemant Malhotra Raja Pramanik Sujay Srinivas Pradyna Kotwal Nikita Mehra Sudeep Gupta Thangarajan Rajkumar Rajiv Sarin Govind Babu Kanakasetty Ajay Bapna B. K. Smruti Rupinder Sekhon Maheboob Basade Sabhayata Gupta Amita Maheshwari S. P. Somashekhar Geeta Kadayaprath Arvind Krishnamurthy Anushree Punia Moushumi Suryavanshi Rekha Gupta Amit Verma Padmaj Kulkarni Purvish Parikh |
| author_facet | Hemant Malhotra Raja Pramanik Sujay Srinivas Pradyna Kotwal Nikita Mehra Sudeep Gupta Thangarajan Rajkumar Rajiv Sarin Govind Babu Kanakasetty Ajay Bapna B. K. Smruti Rupinder Sekhon Maheboob Basade Sabhayata Gupta Amita Maheshwari S. P. Somashekhar Geeta Kadayaprath Arvind Krishnamurthy Anushree Punia Moushumi Suryavanshi Rekha Gupta Amit Verma Padmaj Kulkarni Purvish Parikh |
| author_sort | Hemant Malhotra |
| collection | DOAJ |
| description |
Introduction Hereditary breast and ovarian cancer (HBOC) is driven by mutations in BRCA1/2 and related genes. Their understanding is vital to appropriate management of such patients and at-risk families, including counselling and genetic testing. Several important recent advances have made it necessary to revise the previous recommendations we made for India in 2020. |
| format | Article |
| id | doaj-art-d66a0afd7bd0414c859dfed092f9be55 |
| institution | OA Journals |
| issn | 0971-5851 0975-2129 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-d66a0afd7bd0414c859dfed092f9be552025-08-20T02:32:38ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292025-06-01460323325210.1055/s-0044-1788727Genetic Counselling, Testing, and Management of Hereditary Breast and Ovarian Cancer Syndrome in India: Updated Expert Consensus Recommendations from Indian Society of Medical and Pediatric OncologyHemant Malhotra0https://orcid.org/0000-0001-5613-5375Raja Pramanik1https://orcid.org/0000-0003-0483-6254Sujay Srinivas2https://orcid.org/0000-0001-9981-364XPradyna Kotwal3Nikita Mehra4https://orcid.org/0000-0002-4605-7470Sudeep Gupta5https://orcid.org/0000-0002-6742-6378Thangarajan Rajkumar6Rajiv Sarin7https://orcid.org/0000-0002-6405-8282Govind Babu Kanakasetty8https://orcid.org/0000-0002-1303-2226Ajay Bapna9B. K. Smruti10Rupinder Sekhon11Maheboob Basade12Sabhayata Gupta13Amita Maheshwari14S. P. Somashekhar15Geeta Kadayaprath16https://orcid.org/0000-0002-7084-0107Arvind Krishnamurthy17Anushree Punia18Moushumi Suryavanshi19Rekha Gupta20Amit Verma21Padmaj Kulkarni22Purvish Parikh23Department of Medical Oncology, Sri Ram Cancer Center, Mahatma Gandhi Medical College Hospital, Jaipur, Rajasthan, IndiaDepartment of Medical Oncology, All India Institute of Medical Sciences, New Delhi, Delhi, IndiaDepartment of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, IndiaDepartment of Recombinant DNA Facility, Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, Maharashtra, IndiaDepartment of Medical Oncology, Cancer Institute (WIA - Women's Indian Association), Chennai, Tamil Nadu, IndiaTata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, IndiaDepartment of Molecular Oncology, MedGenome, Bangalore, Karnataka, IndiaDepartment of Cancer Genetics, Tata Memorial Hospital, Mumbai, Maharashtra, IndiaDepartment of Medical Oncology, Healthcare Global Enterprises Ltd. Hospital, Bengaluru, Karnataka, IndiaDepartment of Medical Oncology, Bhagwan Mahaveer Cancer Hospital & Research Centre, Jaipur, Rajasthan, IndiaDepartment of Medical Oncology, Lilavati Hospital and Bombay Hospital Institute of Medical Sciences, Mumbai, Maharashtra, IndiaDepartment of Gynae Oncology, Artemis Cancer Center, Gurugram, Haryana, IndiaDepartment of Medical Oncology, Saifee Hospital, Mumbai, Maharashtra, IndiaDepartment of Gynae Oncology, Medanta the Medicity, Gurugram, Haryana, IndiaDepartment of Gynae Oncology, Tata Memorial Centre and Homi Bhabha National Institute, Maharashtra, Mumbai, IndiaDepartment of Surgical Oncology, Aster International Institute of Oncology, Bengaluru, Karnataka, IndiaDepartment of Surgical Oncology, Max Healthcare, New Delhi, Delhi, IndiaDepartment of Surgical Oncology, Cancer Institute, Chennai, Tamil Nadu, IndiaDepartment of Radiation Oncology, Shri Ram Cancer Centre, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, IndiaDepartment of Molecular Biology, Amrita Institute of Medical Sciences and Research Centre, Faridabad, Utter Pradesh, IndiaDepartment of Medical Genetics, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, IndiaDepartment of Molecular Oncology, Dr. AV Cancer Institute, Gurgaon, Haryana, IndiaDepartment of Medical Oncology, Deenanath Mangeshkar Hospital, Pune, Maharashtra, IndiaDepartment of Clinical Hematology, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, Rajasthan, India Introduction Hereditary breast and ovarian cancer (HBOC) is driven by mutations in BRCA1/2 and related genes. Their understanding is vital to appropriate management of such patients and at-risk families, including counselling and genetic testing. Several important recent advances have made it necessary to revise the previous recommendations we made for India in 2020.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788727hereditary cancertherapydriver mutationsguidelines |
| spellingShingle | Hemant Malhotra Raja Pramanik Sujay Srinivas Pradyna Kotwal Nikita Mehra Sudeep Gupta Thangarajan Rajkumar Rajiv Sarin Govind Babu Kanakasetty Ajay Bapna B. K. Smruti Rupinder Sekhon Maheboob Basade Sabhayata Gupta Amita Maheshwari S. P. Somashekhar Geeta Kadayaprath Arvind Krishnamurthy Anushree Punia Moushumi Suryavanshi Rekha Gupta Amit Verma Padmaj Kulkarni Purvish Parikh Genetic Counselling, Testing, and Management of Hereditary Breast and Ovarian Cancer Syndrome in India: Updated Expert Consensus Recommendations from Indian Society of Medical and Pediatric Oncology Indian Journal of Medical and Paediatric Oncology hereditary cancer therapy driver mutations guidelines |
| title | Genetic Counselling, Testing, and Management of Hereditary Breast and Ovarian Cancer Syndrome in India: Updated Expert Consensus Recommendations from Indian Society of Medical and Pediatric Oncology |
| title_full | Genetic Counselling, Testing, and Management of Hereditary Breast and Ovarian Cancer Syndrome in India: Updated Expert Consensus Recommendations from Indian Society of Medical and Pediatric Oncology |
| title_fullStr | Genetic Counselling, Testing, and Management of Hereditary Breast and Ovarian Cancer Syndrome in India: Updated Expert Consensus Recommendations from Indian Society of Medical and Pediatric Oncology |
| title_full_unstemmed | Genetic Counselling, Testing, and Management of Hereditary Breast and Ovarian Cancer Syndrome in India: Updated Expert Consensus Recommendations from Indian Society of Medical and Pediatric Oncology |
| title_short | Genetic Counselling, Testing, and Management of Hereditary Breast and Ovarian Cancer Syndrome in India: Updated Expert Consensus Recommendations from Indian Society of Medical and Pediatric Oncology |
| title_sort | genetic counselling testing and management of hereditary breast and ovarian cancer syndrome in india updated expert consensus recommendations from indian society of medical and pediatric oncology |
| topic | hereditary cancer therapy driver mutations guidelines |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788727 |
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