Understanding mechanisms of thrombosis and thrombocytopenia with adenoviral SARS-CoV-2 vaccines: a comprehensive synopsis

Background Thrombosis with thrombocytopenia syndrome is a rare condition known to occur spontaneously or after heparin use. With the advent of COVID-19 vaccines during the pandemic, thrombosis with thrombocytopenia syndrome cases emerged post administration of adenoviral vaccines, termed vaccine-ind...

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Main Authors:	Phillip LR Nicolson, Simon T Abrams, Gayatri Amirthalingam, Kevin Brown, Richard J Buka, Mark J Caulfield, Joshua Gardner, David Goldblatt, Charlotte Lovatt, Samantha J Montague, Dean J Naisbitt, Alan Parker, Sue Pavord, Mary E Ramsay, Jonathan AC Sterne, Cathie LM Sudlow, Cheng Hock Toh, Steve P Watson, Guozheng Wang, Angela M Wood, William Whiteley, Munir Pirmohamed
Format:	Article
Language:	English
Published:	NIHR Journals Library 2025-07-01
Series:	Efficacy and Mechanism Evaluation
Subjects:	vitt tts adenovirus azd1222 chadox1 thrombosis pf4 netosis platelets
Online Access:	https://doi.org/10.3310/FFSS9010
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Understanding mechanisms of thrombosis and thrombocytopenia with adenoviral SARS-CoV-2 vaccines: a comprehensive synopsis

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