Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies
Refractory epilepsies are syndromes for which therapies that employ two or more antiepileptic drugs, separately or in association, do not result in control of crisis. Patients may present focal cortical dysplasia or diffuse dysplasia and/or hippocampal atrophic alterations that may not be detectable...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
2013-12-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001300920&lng=en&tlng=en |
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| _version_ | 1849471842635481088 |
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| author | Mauricio Martins Baldissin Edna Marina de Souza |
| author_facet | Mauricio Martins Baldissin Edna Marina de Souza |
| author_sort | Mauricio Martins Baldissin |
| collection | DOAJ |
| description | Refractory epilepsies are syndromes for which therapies that employ two or more antiepileptic drugs, separately or in association, do not result in control of crisis. Patients may present focal cortical dysplasia or diffuse dysplasia and/or hippocampal atrophic alterations that may not be detectable by a simple visual analysis in magnetic resonance imaging. The aim of this study was to evaluate MRI texture in regions of interest located in the hippocampi, limbic association cortex and prefrontal cortex of 20 patients with refractory epilepsy and to compare them with the same areas in 20 healthy individuals, in order to find out if the texture parameters could be related to the presence of the disease. Of the 11 texture parameters calculated, three indicated the existence of statistically significant differences between the studied groups. Such findings suggest the possibility of this technique contributing to studies of refractory epilepsies. |
| format | Article |
| id | doaj-art-d65eea032f114da685c9e9dec086ef15 |
| institution | Kabale University |
| issn | 1678-4227 |
| language | English |
| publishDate | 2013-12-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-d65eea032f114da685c9e9dec086ef152025-08-20T03:24:40ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272013-12-01711292092410.1590/0004-282X20130219S0004-282X2013001300920Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsiesMauricio Martins BaldissinEdna Marina de SouzaRefractory epilepsies are syndromes for which therapies that employ two or more antiepileptic drugs, separately or in association, do not result in control of crisis. Patients may present focal cortical dysplasia or diffuse dysplasia and/or hippocampal atrophic alterations that may not be detectable by a simple visual analysis in magnetic resonance imaging. The aim of this study was to evaluate MRI texture in regions of interest located in the hippocampi, limbic association cortex and prefrontal cortex of 20 patients with refractory epilepsy and to compare them with the same areas in 20 healthy individuals, in order to find out if the texture parameters could be related to the presence of the disease. Of the 11 texture parameters calculated, three indicated the existence of statistically significant differences between the studied groups. Such findings suggest the possibility of this technique contributing to studies of refractory epilepsies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001300920&lng=en&tlng=enepilepsias refratariasressonancia magneticaanalise de textura |
| spellingShingle | Mauricio Martins Baldissin Edna Marina de Souza Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies Arquivos de Neuro-Psiquiatria epilepsias refratarias ressonancia magnetica analise de textura |
| title | Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
| title_full | Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
| title_fullStr | Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
| title_full_unstemmed | Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
| title_short | Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
| title_sort | investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
| topic | epilepsias refratarias ressonancia magnetica analise de textura |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001300920&lng=en&tlng=en |
| work_keys_str_mv | AT mauriciomartinsbaldissin investigationofmagneticresonanceimagingtextureanalysisasanaidtoolforcharacterizationofrefractoryepilepsies AT ednamarinadesouza investigationofmagneticresonanceimagingtextureanalysisasanaidtoolforcharacterizationofrefractoryepilepsies |