Response to Rituximab in a Case of Lupus Associated Digital Ischemia
We report the case of a 38-year-old female patient with systemic lupus erythematosus (SLE) and Jaccoud arthritis (JA) that sequentially developed digital ischemic lesions of the hands. In spite of follow-up treatment with glucocorticoids, immunosuppressant, antiaggregant, and potent vasodilatator ag...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2014/763608 |
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| _version_ | 1850174323774455808 |
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| author | Orhan Küçükşahin Nurşen Düzgün Alexis K. Okoh Emre Kulahçioglu |
| author_facet | Orhan Küçükşahin Nurşen Düzgün Alexis K. Okoh Emre Kulahçioglu |
| author_sort | Orhan Küçükşahin |
| collection | DOAJ |
| description | We report the case of a 38-year-old female patient with systemic lupus erythematosus (SLE) and Jaccoud arthritis (JA) that sequentially developed digital ischemic lesions of the hands. In spite of follow-up treatment with glucocorticoids, immunosuppressant, antiaggregant, and potent vasodilatator agents, a serious progression to digital gangrene over a one-month period was observed. Surprisingly, her nonhealing digital lesions improved after two cycles of rituximab (RTX) administration. |
| format | Article |
| id | doaj-art-d657ebadde9f4bd990fd35cdba852550 |
| institution | OA Journals |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-d657ebadde9f4bd990fd35cdba8525502025-08-20T02:19:40ZengWileyCase Reports in Rheumatology2090-68892090-68972014-01-01201410.1155/2014/763608763608Response to Rituximab in a Case of Lupus Associated Digital IschemiaOrhan Küçükşahin0Nurşen Düzgün1Alexis K. Okoh2Emre Kulahçioglu3Department of Rheumatology, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyDepartment of Rheumatology, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyDepartment of Internal Medicine, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyDepartment of Internal Medicine, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyWe report the case of a 38-year-old female patient with systemic lupus erythematosus (SLE) and Jaccoud arthritis (JA) that sequentially developed digital ischemic lesions of the hands. In spite of follow-up treatment with glucocorticoids, immunosuppressant, antiaggregant, and potent vasodilatator agents, a serious progression to digital gangrene over a one-month period was observed. Surprisingly, her nonhealing digital lesions improved after two cycles of rituximab (RTX) administration.http://dx.doi.org/10.1155/2014/763608 |
| spellingShingle | Orhan Küçükşahin Nurşen Düzgün Alexis K. Okoh Emre Kulahçioglu Response to Rituximab in a Case of Lupus Associated Digital Ischemia Case Reports in Rheumatology |
| title | Response to Rituximab in a Case of Lupus Associated Digital Ischemia |
| title_full | Response to Rituximab in a Case of Lupus Associated Digital Ischemia |
| title_fullStr | Response to Rituximab in a Case of Lupus Associated Digital Ischemia |
| title_full_unstemmed | Response to Rituximab in a Case of Lupus Associated Digital Ischemia |
| title_short | Response to Rituximab in a Case of Lupus Associated Digital Ischemia |
| title_sort | response to rituximab in a case of lupus associated digital ischemia |
| url | http://dx.doi.org/10.1155/2014/763608 |
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