Optimal conditions for vitamin B12 production from Lactobacillus rhamnosus

This research was conducted to study the effect of some nutrients on the growth and production of vitamin B12 by Lactobacillus genus L.rhamnosus, when their ability to produce vitamin B12 was tested under different conditions. The results indicate that a pH of 7 is optimal for vitamin B12 productio...

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Main Authors: Ali Bader Najim, Athraa Harjan Muhsen
Format: Article
Language:English
Published: University of Kufa 2022-12-01
Series:Kufa Journal for Agricultural Sciences
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Online Access:https://journal.uokufa.edu.iq/index.php/kjas/article/view/3687
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author Ali Bader Najim
Athraa Harjan Muhsen
author_facet Ali Bader Najim
Athraa Harjan Muhsen
author_sort Ali Bader Najim
collection DOAJ
description This research was conducted to study the effect of some nutrients on the growth and production of vitamin B12 by Lactobacillus genus L.rhamnosus, when their ability to produce vitamin B12 was tested under different conditions. The results indicate that a pH of 7 is optimal for vitamin B12 production by the bacteria L.rhamnosus and it was found that the optimum incubation temperature for the production of vitamin B12 ranged between 30 - 35 °C, with regard to the effect of the incubation period on the biological activity and productivity of vitamin B12. The results showed that 3 days was the best in the production of vitamin B12. The results also showed that adding the lowest concentration of cobalt chloride gave a high productivity of the vitamin compared to the highest added concentrations and that the best carbon source was sucrose among the three carbon sources that included glucose, fructose, and sucrose, and the results of the study showed that the best nitrogen source It is was peptone compared to yeast extract, which gave the highest production of the vitamin B12.
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spelling doaj-art-d64a6003b3bf403dac7e8acc370dc3de2025-08-20T02:58:36ZengUniversity of KufaKufa Journal for Agricultural Sciences2072-77982312-81862022-12-0114210.36077/kjas/2022/v14i2.3687Optimal conditions for vitamin B12 production from Lactobacillus rhamnosusAli Bader Najim0Athraa Harjan Muhsen 1University of KufaUniversity of Kufa This research was conducted to study the effect of some nutrients on the growth and production of vitamin B12 by Lactobacillus genus L.rhamnosus, when their ability to produce vitamin B12 was tested under different conditions. The results indicate that a pH of 7 is optimal for vitamin B12 production by the bacteria L.rhamnosus and it was found that the optimum incubation temperature for the production of vitamin B12 ranged between 30 - 35 °C, with regard to the effect of the incubation period on the biological activity and productivity of vitamin B12. The results showed that 3 days was the best in the production of vitamin B12. The results also showed that adding the lowest concentration of cobalt chloride gave a high productivity of the vitamin compared to the highest added concentrations and that the best carbon source was sucrose among the three carbon sources that included glucose, fructose, and sucrose, and the results of the study showed that the best nitrogen source It is was peptone compared to yeast extract, which gave the highest production of the vitamin B12. https://journal.uokufa.edu.iq/index.php/kjas/article/view/3687Vitamin B12productionoptimum conditionsLactobacillus rhamnosus
spellingShingle Ali Bader Najim
Athraa Harjan Muhsen
Optimal conditions for vitamin B12 production from Lactobacillus rhamnosus
Kufa Journal for Agricultural Sciences
Vitamin B12production
optimum conditions
Lactobacillus rhamnosus
title Optimal conditions for vitamin B12 production from Lactobacillus rhamnosus
title_full Optimal conditions for vitamin B12 production from Lactobacillus rhamnosus
title_fullStr Optimal conditions for vitamin B12 production from Lactobacillus rhamnosus
title_full_unstemmed Optimal conditions for vitamin B12 production from Lactobacillus rhamnosus
title_short Optimal conditions for vitamin B12 production from Lactobacillus rhamnosus
title_sort optimal conditions for vitamin b12 production from lactobacillus rhamnosus
topic Vitamin B12production
optimum conditions
Lactobacillus rhamnosus
url https://journal.uokufa.edu.iq/index.php/kjas/article/view/3687
work_keys_str_mv AT alibadernajim optimalconditionsforvitaminb12productionfromlactobacillusrhamnosus
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