Evaluation of an innovative, green, and eco-friendly baclofen-loaded niosome (Baclosome) formulation for pain management by transdermal delivery

Evaluation of an innovative, green, and eco-friendly baclofen-loaded niosome (Baclosome) formulation for pain management by transdermal delivery

Objective(s): Baclofen, a muscle relaxant, exhibits limited dermal penetration, restricting its therapeutic efficacy. This study aimed to optimize baclofen delivery using ultrasonically manufactured niosomes (Baclosomes) for improved antinociceptive and anti-inflammatory activity. Materials and Meth...

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Bibliographic Details
Main Authors: Jafar Akbari, Majid Saeedi, Katayoun Morteza-Semnani, Seyede Nastaran Mousavi, Seyyed Mohammad Hassan Hashemi, Seyyed Mobin Rahimnia
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-01-01
Series:Nanomedicine Journal
Subjects:
analgesic
baclofen
green synthesis
niosome
transdermal 
Online Access:https://nmj.mums.ac.ir/article_25016_4089352b199f8fe654925dc3fcf4c16d.pdf
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