MicroRNA-101-3p Suppresses mTOR and Causes Mitochondrial Fragmentation and Cell Degeneration in COPD
Background. Cigarette smoke is assumed to cause the loss of airway wall structure in chronic obstructive pulmonary disease (COPD) by reducing airway smooth muscle cell (ASMC) function. It also modifies mTOR activity, microRNA (miR)-101-3p expression, and mitochondria function. Here, the link between...
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Main Authors: | Lei Fang, Xinggang Wang, Ming Zhang, Petra Khan, Michael Tamm, Michael Roth |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-01-01
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Series: | Canadian Respiratory Journal |
Online Access: | http://dx.doi.org/10.1155/2022/5933324 |
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