Enhanced Tolerance to Antifungals as a General Feature of Rho<sup>−</sup> Mutants in Yeast Species: Implications to Positive Selection of Respiratory Deficiency

Enhanced Tolerance to Antifungals as a General Feature of Rho<sup>−</sup> Mutants in Yeast Species: Implications to Positive Selection of Respiratory Deficiency

Although the mitochondrial genome is an attribute of all eukaryotes, some yeast species (called petite-positive) can replicate without mitochondrial DNA (mtDNA). Strains without mtDNA (known as rho<sup>−</sup> mutants or petite mutants) are respiration-deficient and require fermentable c...

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Bibliographic Details
Main Authors: Zachary Johnson, Farhan Nadim, Mikhajlo K. Zubko
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Microorganisms
Subjects:
antifungals
azoles
<i>Candida</i>
<i>Saccharomyces</i>
rho<sup>−</sup> mutants
petite
Online Access:https://www.mdpi.com/2076-2607/13/1/99
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