The changing epidemiology of paediatric childhood asthma and allergy in different regions of the world
Allergic disorders encompass a variety of conditions including asthma, atopic dermatitis, food allergy, allergic rhinitis, and eosinophilic esophagitis. These atopic disorders are connected via an abnormal host immune response to the environment. A series of longitudinal cross-sectional studies cond...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Allergy |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/falgy.2025.1584928/full |
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| author | D. J. Adamko Kyla J. Hildebrand |
| author_facet | D. J. Adamko Kyla J. Hildebrand |
| author_sort | D. J. Adamko |
| collection | DOAJ |
| description | Allergic disorders encompass a variety of conditions including asthma, atopic dermatitis, food allergy, allergic rhinitis, and eosinophilic esophagitis. These atopic disorders are connected via an abnormal host immune response to the environment. A series of longitudinal cross-sectional studies conducted over the past 3 decades have reported on the epidemiological trends that contribute towards the development of pediatric asthma and allergic disease. Infant birth cohort studies assessing the microbiome have offered clues as to the underlying biological mechanisms and basis for allergic disease. Why this abnormal immune response is occurring is the basis of decades of research and the reasons for this chapter. Our understanding of the biology of the immune system has increased exponentially with the advances in genomic testing, providing further opportunity for targeted treatments and more importantly, primary prevention of atopic disease. |
| format | Article |
| id | doaj-art-d63cdb600bbd44bfa36ef2a4704a06a1 |
| institution | OA Journals |
| issn | 2673-6101 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Allergy |
| spelling | doaj-art-d63cdb600bbd44bfa36ef2a4704a06a12025-08-20T02:20:10ZengFrontiers Media S.A.Frontiers in Allergy2673-61012025-04-01610.3389/falgy.2025.15849281584928The changing epidemiology of paediatric childhood asthma and allergy in different regions of the worldD. J. Adamko0Kyla J. Hildebrand1Division of Respiratory Medicine, Department of Pediatrics, University of Saskatchewan, Saskatchewan, SK, CanadaDivision of Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, CanadaAllergic disorders encompass a variety of conditions including asthma, atopic dermatitis, food allergy, allergic rhinitis, and eosinophilic esophagitis. These atopic disorders are connected via an abnormal host immune response to the environment. A series of longitudinal cross-sectional studies conducted over the past 3 decades have reported on the epidemiological trends that contribute towards the development of pediatric asthma and allergic disease. Infant birth cohort studies assessing the microbiome have offered clues as to the underlying biological mechanisms and basis for allergic disease. Why this abnormal immune response is occurring is the basis of decades of research and the reasons for this chapter. Our understanding of the biology of the immune system has increased exponentially with the advances in genomic testing, providing further opportunity for targeted treatments and more importantly, primary prevention of atopic disease.https://www.frontiersin.org/articles/10.3389/falgy.2025.1584928/fullasthmaallergyepidemiologyinborn error immunityprimary atopic disorders |
| spellingShingle | D. J. Adamko Kyla J. Hildebrand The changing epidemiology of paediatric childhood asthma and allergy in different regions of the world Frontiers in Allergy asthma allergy epidemiology inborn error immunity primary atopic disorders |
| title | The changing epidemiology of paediatric childhood asthma and allergy in different regions of the world |
| title_full | The changing epidemiology of paediatric childhood asthma and allergy in different regions of the world |
| title_fullStr | The changing epidemiology of paediatric childhood asthma and allergy in different regions of the world |
| title_full_unstemmed | The changing epidemiology of paediatric childhood asthma and allergy in different regions of the world |
| title_short | The changing epidemiology of paediatric childhood asthma and allergy in different regions of the world |
| title_sort | changing epidemiology of paediatric childhood asthma and allergy in different regions of the world |
| topic | asthma allergy epidemiology inborn error immunity primary atopic disorders |
| url | https://www.frontiersin.org/articles/10.3389/falgy.2025.1584928/full |
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