Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids
Hearing aids (HAs) are an effective strategy for auditory rehabilitation in patients with peripheral hearing deficits. Yet, the neurophysiological mechanisms behind HA use are still unclear. Thus far, most studies have focused on changes in the auditory system, although it is expected that hearing d...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2018/9303674 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832556574028070912 |
|---|---|
| author | M. R. Pereira-Jorge K. C. Andrade F. X. Palhano-Fontes P. R. B. Diniz M. Sturzbecher A. C. Santos D. B. Araujo |
| author_facet | M. R. Pereira-Jorge K. C. Andrade F. X. Palhano-Fontes P. R. B. Diniz M. Sturzbecher A. C. Santos D. B. Araujo |
| author_sort | M. R. Pereira-Jorge |
| collection | DOAJ |
| description | Hearing aids (HAs) are an effective strategy for auditory rehabilitation in patients with peripheral hearing deficits. Yet, the neurophysiological mechanisms behind HA use are still unclear. Thus far, most studies have focused on changes in the auditory system, although it is expected that hearing deficits affect a number of cognitive systems, notably speech. In the present study, we used audiometric evaluations in 14 patients with bilateral hearing loss before and after one year of continuous HA use and functional magnetic resonance imaging (fMRI) and cortical thickness analysis in 12 and 10 of them compared with a normal hearing control group. Prior to HA fitting, fMRI activity was found reduced in the auditory and language systems and increased in visual and frontal areas, expanding to multimodal integration cortices, such as the superior temporal gyrus, intraparietal sulcus, and insula. One year after rehabilitation with HA, significant audiometric improvement was observed, especially in free-field Speech Reception Threshold (SRT) test and functional gain, a measure of HA efficiency. HA use increased fMRI activity in the auditory and language cortices and multimodal integration areas. Individual fMRI signal changes from all these areas were positively correlated with individual SRT changes. Before rehabilitation, cortical thickness was increased in parts of the prefrontal cortex, precuneus, fusiform gyrus, and middle temporal gyrus. It was reduced in the insula, supramarginal gyrus, medial temporal gyrus, occipital cortex, posterior cingulate cortex, and claustrum. After HA use, increased cortical thickness was observed in multimodal integration regions, particularly the very caudal end of the superior temporal sulcus, the angular gyrus, and the inferior parietal gyrus/superior temporal gyrus/insula. Our data provide the first evidence that one year of HA use is related to functional and anatomical brain changes, notably in auditory and language systems, extending to multimodal cortices. |
| format | Article |
| id | doaj-art-d63bc2c09508411a89c7c1b1621467d1 |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-d63bc2c09508411a89c7c1b1621467d12025-02-03T05:45:09ZengWileyNeural Plasticity2090-59041687-54432018-01-01201810.1155/2018/93036749303674Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing AidsM. R. Pereira-Jorge0K. C. Andrade1F. X. Palhano-Fontes2P. R. B. Diniz3M. Sturzbecher4A. C. Santos5D. B. Araujo6Department of Neuroscience and Behavior, University of São Paulo, Ribeirao Preto, SP, BrazilBrain Institute/Onofre Lopes University Hospital, Federal University of Rio Grande do Norte (UFRN), Natal, RN, BrazilBrain Institute/Onofre Lopes University Hospital, Federal University of Rio Grande do Norte (UFRN), Natal, RN, BrazilDepartment of Internal Medicine, Federal University of Pernambuco, Recife, PE, BrazilDepartment of Neuroscience and Behavior, University of São Paulo, Ribeirao Preto, SP, BrazilDepartment of Neuroscience and Behavior, University of São Paulo, Ribeirao Preto, SP, BrazilBrain Institute/Onofre Lopes University Hospital, Federal University of Rio Grande do Norte (UFRN), Natal, RN, BrazilHearing aids (HAs) are an effective strategy for auditory rehabilitation in patients with peripheral hearing deficits. Yet, the neurophysiological mechanisms behind HA use are still unclear. Thus far, most studies have focused on changes in the auditory system, although it is expected that hearing deficits affect a number of cognitive systems, notably speech. In the present study, we used audiometric evaluations in 14 patients with bilateral hearing loss before and after one year of continuous HA use and functional magnetic resonance imaging (fMRI) and cortical thickness analysis in 12 and 10 of them compared with a normal hearing control group. Prior to HA fitting, fMRI activity was found reduced in the auditory and language systems and increased in visual and frontal areas, expanding to multimodal integration cortices, such as the superior temporal gyrus, intraparietal sulcus, and insula. One year after rehabilitation with HA, significant audiometric improvement was observed, especially in free-field Speech Reception Threshold (SRT) test and functional gain, a measure of HA efficiency. HA use increased fMRI activity in the auditory and language cortices and multimodal integration areas. Individual fMRI signal changes from all these areas were positively correlated with individual SRT changes. Before rehabilitation, cortical thickness was increased in parts of the prefrontal cortex, precuneus, fusiform gyrus, and middle temporal gyrus. It was reduced in the insula, supramarginal gyrus, medial temporal gyrus, occipital cortex, posterior cingulate cortex, and claustrum. After HA use, increased cortical thickness was observed in multimodal integration regions, particularly the very caudal end of the superior temporal sulcus, the angular gyrus, and the inferior parietal gyrus/superior temporal gyrus/insula. Our data provide the first evidence that one year of HA use is related to functional and anatomical brain changes, notably in auditory and language systems, extending to multimodal cortices.http://dx.doi.org/10.1155/2018/9303674 |
| spellingShingle | M. R. Pereira-Jorge K. C. Andrade F. X. Palhano-Fontes P. R. B. Diniz M. Sturzbecher A. C. Santos D. B. Araujo Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids Neural Plasticity |
| title | Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids |
| title_full | Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids |
| title_fullStr | Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids |
| title_full_unstemmed | Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids |
| title_short | Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids |
| title_sort | anatomical and functional mri changes after one year of auditory rehabilitation with hearing aids |
| url | http://dx.doi.org/10.1155/2018/9303674 |
| work_keys_str_mv | AT mrpereirajorge anatomicalandfunctionalmrichangesafteroneyearofauditoryrehabilitationwithhearingaids AT kcandrade anatomicalandfunctionalmrichangesafteroneyearofauditoryrehabilitationwithhearingaids AT fxpalhanofontes anatomicalandfunctionalmrichangesafteroneyearofauditoryrehabilitationwithhearingaids AT prbdiniz anatomicalandfunctionalmrichangesafteroneyearofauditoryrehabilitationwithhearingaids AT msturzbecher anatomicalandfunctionalmrichangesafteroneyearofauditoryrehabilitationwithhearingaids AT acsantos anatomicalandfunctionalmrichangesafteroneyearofauditoryrehabilitationwithhearingaids AT dbaraujo anatomicalandfunctionalmrichangesafteroneyearofauditoryrehabilitationwithhearingaids |