Ultrasound findings in patients with knee osteoarthritis: Relationships with clinical characteristics, radiographic findings and generalized osteoarthritis
Objective: To evaluate the relationship between ultrasound (US) findings and radiographic Kellgren–Lawrence (K/L) grades, symptom severity, and the presence of generalized osteoarthritis (GOA) in patients with knee osteoarthritis (OA), and to identify key US parameters associated with OA severity. M...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
|
| Series: | Osteoarthritis and Cartilage Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2665913125000925 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849240108619792384 |
|---|---|
| author | Ahmet Sumen Kubra Neslihan Kurt Oktay |
| author_facet | Ahmet Sumen Kubra Neslihan Kurt Oktay |
| author_sort | Ahmet Sumen |
| collection | DOAJ |
| description | Objective: To evaluate the relationship between ultrasound (US) findings and radiographic Kellgren–Lawrence (K/L) grades, symptom severity, and the presence of generalized osteoarthritis (GOA) in patients with knee osteoarthritis (OA), and to identify key US parameters associated with OA severity. Methods: This cross-sectional study included 166 patients (332 knees) with radiographically confirmed knee OA. US assessments included medial and lateral meniscus extrusion (MME, LME), suprapatellar effusion, synovitis, femoral cartilage thickness (FCT), femoral cartilage lesions, Baker's cyst, pes anserine bursitis, patellar tendinopathy, and Hoffa's fat pad pathology. K/L grades were determined by radiography. Pain and function were evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). GOA was defined as OA in five or more joints or the presence of Heberden's nodes with additional joint involvement. Results: MME showed a strong correlation with K/L grade (r = 0.954, p < 0.001), with 91.57 % exact agreement. LME showed a moderate correlation (r = 0.693, p < 0.001). GOA was identified in 12.65 % of patients and was independently associated with lower BMI, reduced FCT (<2 mm), and the presence of femoral cartilage lesions. Moderate correlations were observed between K/L grade and pain, WOMAC scores, and symptom duration. Conclusion: MME and FCT measured by US are strong indicators of OA severity and may help identify patients at risk for GOA. US appears to be a practical, radiation-free tool for assessing and monitoring OA progression. Further validation in larger cohorts is recommended. |
| format | Article |
| id | doaj-art-d633578e5e9944c1bcc677ebb820b89f |
| institution | Kabale University |
| issn | 2665-9131 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Osteoarthritis and Cartilage Open |
| spelling | doaj-art-d633578e5e9944c1bcc677ebb820b89f2025-08-20T04:00:43ZengElsevierOsteoarthritis and Cartilage Open2665-91312025-09-017310065610.1016/j.ocarto.2025.100656Ultrasound findings in patients with knee osteoarthritis: Relationships with clinical characteristics, radiographic findings and generalized osteoarthritisAhmet Sumen0Kubra Neslihan Kurt Oktay1BAM Private Physical Medicine and Rehabilitation Clinic, Istanbul, TurkeyUniversity of Health Sciences, Haydarpasa Numune Training and Research Hospital, Department of Physical Medicine and Rehabilitation, Istanbul, Turkey; Corresponding author. Haydarpasa Numune Training and Research Hospital, Selimiye, Tibbiye Cd No:23, Uskudar, 34668, Istanbul, Turkey.Objective: To evaluate the relationship between ultrasound (US) findings and radiographic Kellgren–Lawrence (K/L) grades, symptom severity, and the presence of generalized osteoarthritis (GOA) in patients with knee osteoarthritis (OA), and to identify key US parameters associated with OA severity. Methods: This cross-sectional study included 166 patients (332 knees) with radiographically confirmed knee OA. US assessments included medial and lateral meniscus extrusion (MME, LME), suprapatellar effusion, synovitis, femoral cartilage thickness (FCT), femoral cartilage lesions, Baker's cyst, pes anserine bursitis, patellar tendinopathy, and Hoffa's fat pad pathology. K/L grades were determined by radiography. Pain and function were evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). GOA was defined as OA in five or more joints or the presence of Heberden's nodes with additional joint involvement. Results: MME showed a strong correlation with K/L grade (r = 0.954, p < 0.001), with 91.57 % exact agreement. LME showed a moderate correlation (r = 0.693, p < 0.001). GOA was identified in 12.65 % of patients and was independently associated with lower BMI, reduced FCT (<2 mm), and the presence of femoral cartilage lesions. Moderate correlations were observed between K/L grade and pain, WOMAC scores, and symptom duration. Conclusion: MME and FCT measured by US are strong indicators of OA severity and may help identify patients at risk for GOA. US appears to be a practical, radiation-free tool for assessing and monitoring OA progression. Further validation in larger cohorts is recommended.http://www.sciencedirect.com/science/article/pii/S2665913125000925Knee osteoarthritisUltrasoundKellgren–lawrenceMeniscus extrusionCartilage thicknessGeneralized osteoarthritis |
| spellingShingle | Ahmet Sumen Kubra Neslihan Kurt Oktay Ultrasound findings in patients with knee osteoarthritis: Relationships with clinical characteristics, radiographic findings and generalized osteoarthritis Osteoarthritis and Cartilage Open Knee osteoarthritis Ultrasound Kellgren–lawrence Meniscus extrusion Cartilage thickness Generalized osteoarthritis |
| title | Ultrasound findings in patients with knee osteoarthritis: Relationships with clinical characteristics, radiographic findings and generalized osteoarthritis |
| title_full | Ultrasound findings in patients with knee osteoarthritis: Relationships with clinical characteristics, radiographic findings and generalized osteoarthritis |
| title_fullStr | Ultrasound findings in patients with knee osteoarthritis: Relationships with clinical characteristics, radiographic findings and generalized osteoarthritis |
| title_full_unstemmed | Ultrasound findings in patients with knee osteoarthritis: Relationships with clinical characteristics, radiographic findings and generalized osteoarthritis |
| title_short | Ultrasound findings in patients with knee osteoarthritis: Relationships with clinical characteristics, radiographic findings and generalized osteoarthritis |
| title_sort | ultrasound findings in patients with knee osteoarthritis relationships with clinical characteristics radiographic findings and generalized osteoarthritis |
| topic | Knee osteoarthritis Ultrasound Kellgren–lawrence Meniscus extrusion Cartilage thickness Generalized osteoarthritis |
| url | http://www.sciencedirect.com/science/article/pii/S2665913125000925 |
| work_keys_str_mv | AT ahmetsumen ultrasoundfindingsinpatientswithkneeosteoarthritisrelationshipswithclinicalcharacteristicsradiographicfindingsandgeneralizedosteoarthritis AT kubraneslihankurtoktay ultrasoundfindingsinpatientswithkneeosteoarthritisrelationshipswithclinicalcharacteristicsradiographicfindingsandgeneralizedosteoarthritis |