Risk factors for lower respiratory tract infections in a psychiatric hospital: a retrospective study
Introduction: Locked pediatric inpatient psychiatric units are vulnerable to the emergence and spread of infections, and nosocomial infection, especially respiratory tract infection is potentially a major problem. This study aimed to explore the risk factors for lower respiratory tract infection (L...
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The Journal of Infection in Developing Countries
2023-04-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/17488 |
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| author | Qun Yang Jiancheng Qiu Xing Chen Yalan Hu Hongmei Shen |
| author_facet | Qun Yang Jiancheng Qiu Xing Chen Yalan Hu Hongmei Shen |
| author_sort | Qun Yang |
| collection | DOAJ |
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Introduction: Locked pediatric inpatient psychiatric units are vulnerable to the emergence and spread of infections, and nosocomial infection, especially respiratory tract infection is potentially a major problem. This study aimed to explore the risk factors for lower respiratory tract infection (LRI), in particular, pneumonia.
Methodology: We conducted a retrospective study comprising 4643 patients with schizophrenia (SZ) and 1826 patients with major depressive disorder (MDD), and the chi‐square test was performed to analyze the categorical variables.
Results: The risk ratio for LRI, including pneumonia, in intensive care unit (ICU) was higher than in the general ward, and electroconvulsive therapy (ECT) increased the patients’ susceptibility to LRI and pneumonia. Our data have revealed that patients treated with restraint or clozapine showed a higher prevalence of LRI and pneumonia, and the results indicated that the increased risk of LRI, not pneumonia, was dose‐dependently observed in patients with clozapine treatment.
Conclusions: Our study shows that ICU and ECT treatment were risk factors for LRI and pneumonia in patients with SZ or MDD, and patients with SZ has a prevalence of hospital-acquired infection because of restraint and clozapine treatments.
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| format | Article |
| id | doaj-art-d6319e1a76b24d36bf978c2bd2515db6 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-d6319e1a76b24d36bf978c2bd2515db62025-08-20T02:27:22ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-04-01170410.3855/jidc.17488Risk factors for lower respiratory tract infections in a psychiatric hospital: a retrospective studyQun Yang0Jiancheng Qiu1Xing Chen2Yalan Hu3Hongmei Shen4Laboratory of Biological Psychiatry, Nantong Mental Health Center and Nantong Brain Hospital, Nantong, ChinaLaboratory of Biological Psychiatry, Nantong Mental Health Center and Nantong Brain Hospital, Nantong, ChinaLaboratory of Biological Psychiatry, Nantong Mental Health Center and Nantong Brain Hospital, Nantong, ChinaLaboratory of Biological Psychiatry, Nantong Mental Health Center and Nantong Brain Hospital, Nantong, ChinaLaboratory of Biological Psychiatry, Nantong Mental Health Center and Nantong Brain Hospital, Nantong, China Introduction: Locked pediatric inpatient psychiatric units are vulnerable to the emergence and spread of infections, and nosocomial infection, especially respiratory tract infection is potentially a major problem. This study aimed to explore the risk factors for lower respiratory tract infection (LRI), in particular, pneumonia. Methodology: We conducted a retrospective study comprising 4643 patients with schizophrenia (SZ) and 1826 patients with major depressive disorder (MDD), and the chi‐square test was performed to analyze the categorical variables. Results: The risk ratio for LRI, including pneumonia, in intensive care unit (ICU) was higher than in the general ward, and electroconvulsive therapy (ECT) increased the patients’ susceptibility to LRI and pneumonia. Our data have revealed that patients treated with restraint or clozapine showed a higher prevalence of LRI and pneumonia, and the results indicated that the increased risk of LRI, not pneumonia, was dose‐dependently observed in patients with clozapine treatment. Conclusions: Our study shows that ICU and ECT treatment were risk factors for LRI and pneumonia in patients with SZ or MDD, and patients with SZ has a prevalence of hospital-acquired infection because of restraint and clozapine treatments. https://jidc.org/index.php/journal/article/view/17488Nosocomial infection; low respiratory tract infection; pneumonia; risk factors; schizophrenia; major depressive disorder. |
| spellingShingle | Qun Yang Jiancheng Qiu Xing Chen Yalan Hu Hongmei Shen Risk factors for lower respiratory tract infections in a psychiatric hospital: a retrospective study Journal of Infection in Developing Countries Nosocomial infection; low respiratory tract infection; pneumonia; risk factors; schizophrenia; major depressive disorder. |
| title | Risk factors for lower respiratory tract infections in a psychiatric hospital: a retrospective study |
| title_full | Risk factors for lower respiratory tract infections in a psychiatric hospital: a retrospective study |
| title_fullStr | Risk factors for lower respiratory tract infections in a psychiatric hospital: a retrospective study |
| title_full_unstemmed | Risk factors for lower respiratory tract infections in a psychiatric hospital: a retrospective study |
| title_short | Risk factors for lower respiratory tract infections in a psychiatric hospital: a retrospective study |
| title_sort | risk factors for lower respiratory tract infections in a psychiatric hospital a retrospective study |
| topic | Nosocomial infection; low respiratory tract infection; pneumonia; risk factors; schizophrenia; major depressive disorder. |
| url | https://jidc.org/index.php/journal/article/view/17488 |
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