Delivered baicalein immunomodulatory hydrogel with dual properties of pH-responsive and anti-infection orchestrates pro-regenerative response of macrophages for enhanced hypertrophic scars therapy

Antibiotic-resistant bacterial infections in skin wounds can cause persistent inflammatory responses, which may lead to severe hypertrophic scarring. In this study, a pH-responsive antibacterial hydrogel composed of phenylboronic acid-grafted chitosan (PBCS) and tannic acid (TA) was developed to ach...

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Bibliographic Details
Main Authors: Fengqing Shang, Yanling Qu, Yu Li, Lingjuan Dong, Dan Liu, Zhe Wang, Afeng Li, Yinghui Li, Dan Zhang, Leiguo Ming, Ronghua Jin
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Materials Today Bio
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425007306
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