GRK5 intronic (CA)n polymorphisms associated with type 2 diabetes in Chinese Hainan Island.

GRK5 intronic (CA)n polymorphisms associated with type 2 diabetes in Chinese Hainan Island.

A genome-wide association study had showed G-protein-coupled receptor kinase 5 (GRK5) rs10886471 was related to the risk of type 2 diabetes mellitus (T2DM) through upregulated GRK5 mRNA expression. Rs10886471 is located in the intron region of GRK5. However, the mechanism by which intronic SNP affec...

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Bibliographic Details
Main Authors: Zhenfang Xia, Tubao Yang, Zhuansuo Wang, Jianping Dong, Chunyan Liang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090597&type=printable
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