Do stylet needles improve diagnostic accuracy in thyroid fine-needle aspiration? A retrospective analysis
Abstract Background Compared to syringe needles, stylet needles are hypothesized to enhance the specimen adequacy of thyroid fine needle aspiration (FNA) by potentially minimizing blood contamination. However, this hypothesis lacks robust evidence for substantiation. Additionally, the substantially...
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BMC
2025-06-01
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| Series: | BMC Endocrine Disorders |
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| Online Access: | https://doi.org/10.1186/s12902-025-01971-8 |
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| author | Pengfei Luo Wei Ma Dahai Jiao |
| author_facet | Pengfei Luo Wei Ma Dahai Jiao |
| author_sort | Pengfei Luo |
| collection | DOAJ |
| description | Abstract Background Compared to syringe needles, stylet needles are hypothesized to enhance the specimen adequacy of thyroid fine needle aspiration (FNA) by potentially minimizing blood contamination. However, this hypothesis lacks robust evidence for substantiation. Additionally, the substantially higher cost of stylet needles (often several orders of magnitude greater than syringe needles) raises concerns about increased procedural expenses. This study aimed to compare the outcomes of thyroid FNA using stylet versus syringe needles in a large cohort. Methods This retrospective analysis included 4793 FNA procedures (2088 using stylet needles and 2705 using syringe needles) performed by five operators. The primary outcome was specimen adequacy. Secondary outcomes included sensitivity, specificity, diagnostic accuracy, positive predictive value (PPV), and negative predictive value (NPV). Results No significant differences were found between stylet and syringe needle FNA for specimen adequacy (85.34% vs. 87.13%), sensitivity (95.24% vs. 96.99%), specificity (78.57% vs. 78.05%), diagnostic accuracy (93.96% vs. 95.07%), PPV (98.16% vs. 97.52%), or NPV (57.89% vs. 74.42%). Performance metrics for both methods were also not significantly different within each operator’s data. Conclusion This study found no significant benefit of stylet needles over syringe needles regarding specimen adequacy or diagnostic yield in thyroid FNA. Clinical trial number Not applicable. |
| format | Article |
| id | doaj-art-d6187a940be04c058b4cef67914bb84b |
| institution | OA Journals |
| issn | 1472-6823 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | BMC |
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| series | BMC Endocrine Disorders |
| spelling | doaj-art-d6187a940be04c058b4cef67914bb84b2025-08-20T02:06:27ZengBMCBMC Endocrine Disorders1472-68232025-06-012511910.1186/s12902-025-01971-8Do stylet needles improve diagnostic accuracy in thyroid fine-needle aspiration? A retrospective analysisPengfei Luo0Wei Ma1Dahai Jiao2Department of General Surgery, Fuyang People’s HospitalDepartment of General Surgery, Fuyang People’s HospitalDepartment of General Surgery, Fuyang People’s HospitalAbstract Background Compared to syringe needles, stylet needles are hypothesized to enhance the specimen adequacy of thyroid fine needle aspiration (FNA) by potentially minimizing blood contamination. However, this hypothesis lacks robust evidence for substantiation. Additionally, the substantially higher cost of stylet needles (often several orders of magnitude greater than syringe needles) raises concerns about increased procedural expenses. This study aimed to compare the outcomes of thyroid FNA using stylet versus syringe needles in a large cohort. Methods This retrospective analysis included 4793 FNA procedures (2088 using stylet needles and 2705 using syringe needles) performed by five operators. The primary outcome was specimen adequacy. Secondary outcomes included sensitivity, specificity, diagnostic accuracy, positive predictive value (PPV), and negative predictive value (NPV). Results No significant differences were found between stylet and syringe needle FNA for specimen adequacy (85.34% vs. 87.13%), sensitivity (95.24% vs. 96.99%), specificity (78.57% vs. 78.05%), diagnostic accuracy (93.96% vs. 95.07%), PPV (98.16% vs. 97.52%), or NPV (57.89% vs. 74.42%). Performance metrics for both methods were also not significantly different within each operator’s data. Conclusion This study found no significant benefit of stylet needles over syringe needles regarding specimen adequacy or diagnostic yield in thyroid FNA. Clinical trial number Not applicable.https://doi.org/10.1186/s12902-025-01971-8Fine-needle aspirationThyroid noduleNeedleAdequacy |
| spellingShingle | Pengfei Luo Wei Ma Dahai Jiao Do stylet needles improve diagnostic accuracy in thyroid fine-needle aspiration? A retrospective analysis BMC Endocrine Disorders Fine-needle aspiration Thyroid nodule Needle Adequacy |
| title | Do stylet needles improve diagnostic accuracy in thyroid fine-needle aspiration? A retrospective analysis |
| title_full | Do stylet needles improve diagnostic accuracy in thyroid fine-needle aspiration? A retrospective analysis |
| title_fullStr | Do stylet needles improve diagnostic accuracy in thyroid fine-needle aspiration? A retrospective analysis |
| title_full_unstemmed | Do stylet needles improve diagnostic accuracy in thyroid fine-needle aspiration? A retrospective analysis |
| title_short | Do stylet needles improve diagnostic accuracy in thyroid fine-needle aspiration? A retrospective analysis |
| title_sort | do stylet needles improve diagnostic accuracy in thyroid fine needle aspiration a retrospective analysis |
| topic | Fine-needle aspiration Thyroid nodule Needle Adequacy |
| url | https://doi.org/10.1186/s12902-025-01971-8 |
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