Comparison of plasma p-tau217 and p-tau181 in predicting amyloid positivity and prognosis among Korean memory clinic patients

Comparison of plasma p-tau217 and p-tau181 in predicting amyloid positivity and prognosis among Korean memory clinic patients

Abstract We investigated plasma phosphorylated tau217 (p-tau217) and p-tau181 efficacy in predicting positive amyloid positron emission tomography (PET) results and cognitive stage transitions. Plasma p-tau217 and p-tau181 were measured in participants who were cognitively unimpaired (CU, n = 121),...

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Main Authors: Hyuk Sung Kwon, Mina Hwang, Seong-Ho Koh, Seong Hye Choi, Jae-Hong Lee, Hyung-Ji Kim, So-Hee Park, Hyun-Hee Park, Jee Hyang Jeong, Myung Hoon Han, Ji Young Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
p-tau181
p-tau217
APOE
Amyloid beta
Amyloid positron emission tomography
Alzheimer’s disease
Online Access:https://doi.org/10.1038/s41598-025-90232-8
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