Functional disability among Behçet’s disease patients: its relation to disease activity, depression, and fatigue
Abstract Background Patients with Behçet’s disease (BD) who exhibit all of the physical and psychological symptoms and signs are likely to experience difficulties with daily living activities related to BD. The current study aimed to assess several factors that may be related to functional disabilit...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2024-12-01
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| Series: | Egyptian Rheumatology and Rehabilitation |
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| Online Access: | https://doi.org/10.1186/s43166-024-00293-2 |
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| author | Ghada A. Dawa Mirvet A. El Toukhey Nagwa A. Sherby Shaimaa A. Mohamed |
| author_facet | Ghada A. Dawa Mirvet A. El Toukhey Nagwa A. Sherby Shaimaa A. Mohamed |
| author_sort | Ghada A. Dawa |
| collection | DOAJ |
| description | Abstract Background Patients with Behçet’s disease (BD) who exhibit all of the physical and psychological symptoms and signs are likely to experience difficulties with daily living activities related to BD. The current study aimed to assess several factors that may be related to functional disability among BD patients studying these factors and targeting them to increase physical and mental activity as well as functional ability in the future. Results Seventy-four BD patients were included in our study and they were 51 males and 23 females. BD patients had significantly higher Hospital Anxiety Depression Scale component for depression, and for anxiety, and Multidimensional Assessment of Fatigue scores than the healthy controls (P = 0.005, P < 0.001, and P < 0.001 respectively). A positive correlation was found significantly between the Modified Health Assessment Questionnaire and age (r = 0.2, P = 0.03), the duration of disease (r = 0.3, P = 0.01), disease activity (P = 0.008), and among patients with vascular (P = 0.02) and neurological affection (P = 0.002). Also, there was a highly significant positive correlation with anxiety, depression, and fatigue (P < 0.001). Conclusion In BD patients, realizing the relationships between increased disability and aging, female sex, long disease duration, vascular and neurological involvement, different indices of activity, fatigue, anxiety, and depression was detected. Disease activity is one of the most important factors causing disability that should be controlled. Screening for depression, anxiety, and fatigue plus proper treatment is highly valued in promoting patient’s coping with the disease. |
| format | Article |
| id | doaj-art-d613ede251e94c71ba442a30ccab9f6f |
| institution | DOAJ |
| issn | 2090-3235 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Egyptian Rheumatology and Rehabilitation |
| spelling | doaj-art-d613ede251e94c71ba442a30ccab9f6f2025-08-20T02:43:36ZengSpringerOpenEgyptian Rheumatology and Rehabilitation2090-32352024-12-0151111010.1186/s43166-024-00293-2Functional disability among Behçet’s disease patients: its relation to disease activity, depression, and fatigueGhada A. Dawa0Mirvet A. El Toukhey1Nagwa A. Sherby2Shaimaa A. Mohamed3Rheumatology & Rehabilitation Department, Faculty of Medicine, Zagazig UniversityRheumatology & Rehabilitation Department, Faculty of Medicine, Zagazig UniversityRheumatology & Rehabilitation Department, Faculty of Medicine, Zagazig UniversityRheumatology & Rehabilitation Department, Faculty of Medicine, Zagazig UniversityAbstract Background Patients with Behçet’s disease (BD) who exhibit all of the physical and psychological symptoms and signs are likely to experience difficulties with daily living activities related to BD. The current study aimed to assess several factors that may be related to functional disability among BD patients studying these factors and targeting them to increase physical and mental activity as well as functional ability in the future. Results Seventy-four BD patients were included in our study and they were 51 males and 23 females. BD patients had significantly higher Hospital Anxiety Depression Scale component for depression, and for anxiety, and Multidimensional Assessment of Fatigue scores than the healthy controls (P = 0.005, P < 0.001, and P < 0.001 respectively). A positive correlation was found significantly between the Modified Health Assessment Questionnaire and age (r = 0.2, P = 0.03), the duration of disease (r = 0.3, P = 0.01), disease activity (P = 0.008), and among patients with vascular (P = 0.02) and neurological affection (P = 0.002). Also, there was a highly significant positive correlation with anxiety, depression, and fatigue (P < 0.001). Conclusion In BD patients, realizing the relationships between increased disability and aging, female sex, long disease duration, vascular and neurological involvement, different indices of activity, fatigue, anxiety, and depression was detected. Disease activity is one of the most important factors causing disability that should be controlled. Screening for depression, anxiety, and fatigue plus proper treatment is highly valued in promoting patient’s coping with the disease.https://doi.org/10.1186/s43166-024-00293-2Behçet’s diseaseDisabilityAnxietyDepressionFatigue |
| spellingShingle | Ghada A. Dawa Mirvet A. El Toukhey Nagwa A. Sherby Shaimaa A. Mohamed Functional disability among Behçet’s disease patients: its relation to disease activity, depression, and fatigue Egyptian Rheumatology and Rehabilitation Behçet’s disease Disability Anxiety Depression Fatigue |
| title | Functional disability among Behçet’s disease patients: its relation to disease activity, depression, and fatigue |
| title_full | Functional disability among Behçet’s disease patients: its relation to disease activity, depression, and fatigue |
| title_fullStr | Functional disability among Behçet’s disease patients: its relation to disease activity, depression, and fatigue |
| title_full_unstemmed | Functional disability among Behçet’s disease patients: its relation to disease activity, depression, and fatigue |
| title_short | Functional disability among Behçet’s disease patients: its relation to disease activity, depression, and fatigue |
| title_sort | functional disability among behcet s disease patients its relation to disease activity depression and fatigue |
| topic | Behçet’s disease Disability Anxiety Depression Fatigue |
| url | https://doi.org/10.1186/s43166-024-00293-2 |
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