Low levels of soluble DPP4 among Saudis may have constituted a risk factor for MERS endemicity.
Most of the cases of Middle East respiratory syndrome coronavirus (MERS-CoV) were reported in Saudi Arabia. Dipeptidyl peptidase-4 (DPP4) was identified as the receptor for the virus. The level of soluble DPP4 (sDPP4) was found to be reduced in MERS-CoV infected patients while high levels of sDPP4 w...
Saved in:
| Main Authors: | Khaled R Alkharsah, Salma Ali Aljaroodi, Jawad Ur Rahman, Awatif N Alnafie, Reem Al Dossary, Reem Y Aljindan, Amani M Alnimr, Jamal Hussen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0266603&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Modulatory Effects of the Recombinant Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike S1 Subunit Protein on the Phenotype of Camel Monocyte-Derived Macrophages
by: Jamal Hussen, et al.
Published: (2025-03-01) -
Transmission dynamics of MERS-CoV in a transgenic human DPP4 mouse model
by: Neeltje van Doremalen, et al.
Published: (2024-08-01) -
Middle East respiratory syndrome coronavirus (MERS-CoV) internalization does not rely on DPP4 cytoplasmic tail signaling
by: Karthika Thankamani, et al.
Published: (2024-12-01) -
Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors
by: Leonard Sewald, et al.
Published: (2025-04-01) -
DPP8 and DPP9 promote tubular epithelial cell ferroptosis in acute kidney injury
by: Kexin Guan, et al.
Published: (2025-07-01)