A Prospective Study of Immune Response After COVID-19 or Vaccination and Correlation Between Avidity Index and Neutralizing Capacity
Conclusion: Anti-spike IgG levels can be used as an estimation of the neutralizing titer, with the avidity index not contributing to a better estimation. There is a stronger initial immune response after vaccination, compared with natural infection. However, specific antibody levels decline over tim...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Advances in Virology |
| Online Access: | http://dx.doi.org/10.1155/av/2265813 |
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| _version_ | 1849706413659521024 |
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| author | Emma Löfström Anna Eringfält Arne Kötz Wanda Christ Stefan Kunkel Johan Tham Jonas Klingström Johan Undén |
| author_facet | Emma Löfström Anna Eringfält Arne Kötz Wanda Christ Stefan Kunkel Johan Tham Jonas Klingström Johan Undén |
| author_sort | Emma Löfström |
| collection | DOAJ |
| description | Conclusion: Anti-spike IgG levels can be used as an estimation of the neutralizing titer, with the avidity index not contributing to a better estimation. There is a stronger initial immune response after vaccination, compared with natural infection. However, specific antibody levels decline over time, highlighting the importance of vaccine boosters. |
| format | Article |
| id | doaj-art-d6063c896bc443e888e34c0784c081ca |
| institution | DOAJ |
| issn | 1687-8647 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Virology |
| spelling | doaj-art-d6063c896bc443e888e34c0784c081ca2025-08-20T03:16:12ZengWileyAdvances in Virology1687-86472025-01-01202510.1155/av/2265813A Prospective Study of Immune Response After COVID-19 or Vaccination and Correlation Between Avidity Index and Neutralizing CapacityEmma Löfström0Anna Eringfält1Arne Kötz2Wanda Christ3Stefan Kunkel4Johan Tham5Jonas Klingström6Johan Undén7Department of Clinical SciencesDepartment of Clinical MicrobiologyDepartment of Clinical MicrobiologyDepartment of Medicine HuddingeDepartment of Research and DevelopmentDepartment of Translational MedicineDepartment of Medicine HuddingeDepartment of Operation and Intensive CareConclusion: Anti-spike IgG levels can be used as an estimation of the neutralizing titer, with the avidity index not contributing to a better estimation. There is a stronger initial immune response after vaccination, compared with natural infection. However, specific antibody levels decline over time, highlighting the importance of vaccine boosters.http://dx.doi.org/10.1155/av/2265813 |
| spellingShingle | Emma Löfström Anna Eringfält Arne Kötz Wanda Christ Stefan Kunkel Johan Tham Jonas Klingström Johan Undén A Prospective Study of Immune Response After COVID-19 or Vaccination and Correlation Between Avidity Index and Neutralizing Capacity Advances in Virology |
| title | A Prospective Study of Immune Response After COVID-19 or Vaccination and Correlation Between Avidity Index and Neutralizing Capacity |
| title_full | A Prospective Study of Immune Response After COVID-19 or Vaccination and Correlation Between Avidity Index and Neutralizing Capacity |
| title_fullStr | A Prospective Study of Immune Response After COVID-19 or Vaccination and Correlation Between Avidity Index and Neutralizing Capacity |
| title_full_unstemmed | A Prospective Study of Immune Response After COVID-19 or Vaccination and Correlation Between Avidity Index and Neutralizing Capacity |
| title_short | A Prospective Study of Immune Response After COVID-19 or Vaccination and Correlation Between Avidity Index and Neutralizing Capacity |
| title_sort | prospective study of immune response after covid 19 or vaccination and correlation between avidity index and neutralizing capacity |
| url | http://dx.doi.org/10.1155/av/2265813 |
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