Alteration in Taste Perception among Young Children following the Use of Oral Irrigants in Pulpectomy Procedure: A Randomised Controlled Trial

Introduction: The impact of oral irrigants on taste perception during pulpectomy procedures focuses on how these sensory experiences affect patient comfort and cooperation. This study aims to identify child-friendly irrigants with natural taste profiles that minimise discomfort and enhance procedura...

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Main Authors: S Praveen Kumar, R Ramesh
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2025-06-01
Series:Journal of Clinical and Diagnostic Research
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Online Access:https://jcdr.net/articles/PDF/21092/77496_CE[Ra1]_F(SS)_QC(PS_SS)_PF1(Rf_SS)_PFA(IS)_PN(IS).pdf
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author S Praveen Kumar
R Ramesh
author_facet S Praveen Kumar
R Ramesh
author_sort S Praveen Kumar
collection DOAJ
description Introduction: The impact of oral irrigants on taste perception during pulpectomy procedures focuses on how these sensory experiences affect patient comfort and cooperation. This study aims to identify child-friendly irrigants with natural taste profiles that minimise discomfort and enhance procedural success. Aim: This study evaluated the effects of different oral irrigants-chlorine dioxide, Saline, Chlorhexidine Gluconate, and Sodium Hypochlorite-on taste perception in children undergoing pulpectomy procedures. Materials and Methods: A randomised controlled trial was conducted at Saveetha Dental College and Hospital from July to December 2024, involving 100 children aged 6-9 years undergoing pulpectomy procedures. Participants were randomly assigned to four groups based on the irrigant used: chlorine dioxide, saline, chlorhexidine gluconate, and sodium hypochlorite. The study assessed taste perception using a 5-point Likert scale and a validated questionnaire at baseline and during the second visit. Demographic parameters such as age, gender, and oral health metrics were recorded to ensure group homogeneity. Statistical analysis included paired t-tests, one-way Analysis of Variance (ANOVA), and effect size estimation, with a p-value of <0.05 considered significant. Results: Significant differences in taste alteration scores were observed across the four oral irrigants. Chlorine dioxide exhibited the most substantial reduction in taste alteration scores from T0 (2.96±1.24) to T1 (1.40±0.76), followed by Saline (T0: 3.12±1.01; T1: 2.24±1.27). In contrast, chlorhexidine and sodium hypochlorite showed minimal changes between baseline and follow-up scores. ANOVA revealed statistically significant differences in taste perceptions for chlorine dioxide (p<0.001), Saline (p=0.007), and Chlorhexidine (p=0.033), while Sodium Hypochlorite exhibited borderline significance (p=0.057). Effect size analysis indicated that chlorine dioxide (Eta²=0.398) had the largest impact, particularly influencing sweetness and bitterness perceptions, which played a crucial role in the overall treatment experience. Conclusion: The study underscores the importance of selecting irrigants that balance clinical efficacy with sensory acceptability. Chlorine dioxide demonstrated the greatest impact on taste alteration, necessitating the development of paediatric-friendly formulations to enhance patient cooperation and comfort.
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spelling doaj-art-d6048b0d305c4fedb8fe5923743e73ba2025-08-20T02:34:47ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-06-01196ZC21ZC2610.7860/JCDR/2025/77496.21092Alteration in Taste Perception among Young Children following the Use of Oral Irrigants in Pulpectomy Procedure: A Randomised Controlled TrialS Praveen Kumar0R Ramesh1Resident Intern, Department of Paediatric Dentistry, Saveetha Dental College, SIMATS University, Chennai, Tamil Nadu, India.Senior Lecturer, Department of Paediatric Dentistry, Saveetha Dental College, SIMATS University, Chennai, Tamil Nadu, India.Introduction: The impact of oral irrigants on taste perception during pulpectomy procedures focuses on how these sensory experiences affect patient comfort and cooperation. This study aims to identify child-friendly irrigants with natural taste profiles that minimise discomfort and enhance procedural success. Aim: This study evaluated the effects of different oral irrigants-chlorine dioxide, Saline, Chlorhexidine Gluconate, and Sodium Hypochlorite-on taste perception in children undergoing pulpectomy procedures. Materials and Methods: A randomised controlled trial was conducted at Saveetha Dental College and Hospital from July to December 2024, involving 100 children aged 6-9 years undergoing pulpectomy procedures. Participants were randomly assigned to four groups based on the irrigant used: chlorine dioxide, saline, chlorhexidine gluconate, and sodium hypochlorite. The study assessed taste perception using a 5-point Likert scale and a validated questionnaire at baseline and during the second visit. Demographic parameters such as age, gender, and oral health metrics were recorded to ensure group homogeneity. Statistical analysis included paired t-tests, one-way Analysis of Variance (ANOVA), and effect size estimation, with a p-value of <0.05 considered significant. Results: Significant differences in taste alteration scores were observed across the four oral irrigants. Chlorine dioxide exhibited the most substantial reduction in taste alteration scores from T0 (2.96±1.24) to T1 (1.40±0.76), followed by Saline (T0: 3.12±1.01; T1: 2.24±1.27). In contrast, chlorhexidine and sodium hypochlorite showed minimal changes between baseline and follow-up scores. ANOVA revealed statistically significant differences in taste perceptions for chlorine dioxide (p<0.001), Saline (p=0.007), and Chlorhexidine (p=0.033), while Sodium Hypochlorite exhibited borderline significance (p=0.057). Effect size analysis indicated that chlorine dioxide (Eta²=0.398) had the largest impact, particularly influencing sweetness and bitterness perceptions, which played a crucial role in the overall treatment experience. Conclusion: The study underscores the importance of selecting irrigants that balance clinical efficacy with sensory acceptability. Chlorine dioxide demonstrated the greatest impact on taste alteration, necessitating the development of paediatric-friendly formulations to enhance patient cooperation and comfort.https://jcdr.net/articles/PDF/21092/77496_CE[Ra1]_F(SS)_QC(PS_SS)_PF1(Rf_SS)_PFA(IS)_PN(IS).pdfdental care for childrenpaediatric dentistrypatient compliancesensory thresholds
spellingShingle S Praveen Kumar
R Ramesh
Alteration in Taste Perception among Young Children following the Use of Oral Irrigants in Pulpectomy Procedure: A Randomised Controlled Trial
Journal of Clinical and Diagnostic Research
dental care for children
paediatric dentistry
patient compliance
sensory thresholds
title Alteration in Taste Perception among Young Children following the Use of Oral Irrigants in Pulpectomy Procedure: A Randomised Controlled Trial
title_full Alteration in Taste Perception among Young Children following the Use of Oral Irrigants in Pulpectomy Procedure: A Randomised Controlled Trial
title_fullStr Alteration in Taste Perception among Young Children following the Use of Oral Irrigants in Pulpectomy Procedure: A Randomised Controlled Trial
title_full_unstemmed Alteration in Taste Perception among Young Children following the Use of Oral Irrigants in Pulpectomy Procedure: A Randomised Controlled Trial
title_short Alteration in Taste Perception among Young Children following the Use of Oral Irrigants in Pulpectomy Procedure: A Randomised Controlled Trial
title_sort alteration in taste perception among young children following the use of oral irrigants in pulpectomy procedure a randomised controlled trial
topic dental care for children
paediatric dentistry
patient compliance
sensory thresholds
url https://jcdr.net/articles/PDF/21092/77496_CE[Ra1]_F(SS)_QC(PS_SS)_PF1(Rf_SS)_PFA(IS)_PN(IS).pdf
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