Controllable synthesis of fluorescent silver nanoparticles with different length oligonucleotides

Abstract Silver nanomaterials have become important research topics in recent years. As a new type of fluorescent material, silver nanomaterials have been applied to fluorescent sensors, bioimaging and materials targeting cancer cells. Here, an approach to the oligonucleotide‐templated controllable...

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Main Authors: Wenhui Bao, Jun Ai, Lu Ga
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:IET Nanobiotechnology
Online Access:https://doi.org/10.1049/nbt2.12049
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author Wenhui Bao
Jun Ai
Lu Ga
author_facet Wenhui Bao
Jun Ai
Lu Ga
author_sort Wenhui Bao
collection DOAJ
description Abstract Silver nanomaterials have become important research topics in recent years. As a new type of fluorescent material, silver nanomaterials have been applied to fluorescent sensors, bioimaging and materials targeting cancer cells. Here, an approach to the oligonucleotide‐templated controllable formation of fluorescent Ag nanomaterials is reported. In this experiment, silver nanoparticles (NPs) were synthesised from oligonucleotides chains, sodium borohydride (NaBH4) and silver nitrate (AgNO3) by changing the molar ratio of DNA to sodium borohydride (NaBH4) and silver nitrate (AgNO3). Fluorescent assay and transmission electron microscopy were used to characterise the silver NPs. The optimal selection of DNA chains with different lengths as templates for the synthesis of silver NPs was found. This work successfully develops the capping oligonucleotides scaffolds of silver nanoclusters.
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publishDate 2021-07-01
publisher Wiley
record_format Article
series IET Nanobiotechnology
spelling doaj-art-d5ffd87bb76c434b9f0388b4f106d7992025-08-20T03:23:38ZengWileyIET Nanobiotechnology1751-87411751-875X2021-07-0115551251810.1049/nbt2.12049Controllable synthesis of fluorescent silver nanoparticles with different length oligonucleotidesWenhui Bao0Jun Ai1Lu Ga2College of Chemistry and Environmental Science Inner Mongolia Key Laboratory of Environmental Chemistry Inner Mongolia Normal University Hohhot ChinaCollege of Chemistry and Environmental Science Inner Mongolia Key Laboratory of Environmental Chemistry Inner Mongolia Normal University Hohhot ChinaCollege of Pharmacy Inner Mongolia Medical University Hohhot ChinaAbstract Silver nanomaterials have become important research topics in recent years. As a new type of fluorescent material, silver nanomaterials have been applied to fluorescent sensors, bioimaging and materials targeting cancer cells. Here, an approach to the oligonucleotide‐templated controllable formation of fluorescent Ag nanomaterials is reported. In this experiment, silver nanoparticles (NPs) were synthesised from oligonucleotides chains, sodium borohydride (NaBH4) and silver nitrate (AgNO3) by changing the molar ratio of DNA to sodium borohydride (NaBH4) and silver nitrate (AgNO3). Fluorescent assay and transmission electron microscopy were used to characterise the silver NPs. The optimal selection of DNA chains with different lengths as templates for the synthesis of silver NPs was found. This work successfully develops the capping oligonucleotides scaffolds of silver nanoclusters.https://doi.org/10.1049/nbt2.12049
spellingShingle Wenhui Bao
Jun Ai
Lu Ga
Controllable synthesis of fluorescent silver nanoparticles with different length oligonucleotides
IET Nanobiotechnology
title Controllable synthesis of fluorescent silver nanoparticles with different length oligonucleotides
title_full Controllable synthesis of fluorescent silver nanoparticles with different length oligonucleotides
title_fullStr Controllable synthesis of fluorescent silver nanoparticles with different length oligonucleotides
title_full_unstemmed Controllable synthesis of fluorescent silver nanoparticles with different length oligonucleotides
title_short Controllable synthesis of fluorescent silver nanoparticles with different length oligonucleotides
title_sort controllable synthesis of fluorescent silver nanoparticles with different length oligonucleotides
url https://doi.org/10.1049/nbt2.12049
work_keys_str_mv AT wenhuibao controllablesynthesisoffluorescentsilvernanoparticleswithdifferentlengtholigonucleotides
AT junai controllablesynthesisoffluorescentsilvernanoparticleswithdifferentlengtholigonucleotides
AT luga controllablesynthesisoffluorescentsilvernanoparticleswithdifferentlengtholigonucleotides