Aquaporin-7 Deficiency Attenuates Liver Fibrosis by Inhibiting the Activation and Proliferation of Hepatic Stellate CellsSummary

Aquaporin-7 Deficiency Attenuates Liver Fibrosis by Inhibiting the Activation and Proliferation of Hepatic Stellate CellsSummary

Background & Aims: Aquaporin-7 (Aqp7) is an aquaglyceroporin that provides transmembrane gateway of water, glycerol, and hydrogen peroxide (H2O2). Analysis of the Gene Expression Omnibus (GEO) database revealed upregulation of hepatic AQP7 expression in liver fibrosis patients. This study ai...

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Bibliographic Details
Main Authors: Junqi Zhang, Yijun Ma, Yu Wang, Chi Zhang, Peng Chen, Qing Ye, Yueyue Lei, Yanghao Li, Bo Zhang, Tonghui Ma
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Aqp7
Autophagy
Glycerol
H2O2
HSCs
Liver Fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X24002042
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