Challenges and future directions of AIRR-seq-based diagnostics

Challenges and future directions of AIRR-seq-based diagnostics

Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) is a promising diagnostic method across various clinical conditions, yet its widespread implementation faces several challenges. This perspective examines the current landscape of AIRR-seq diagnostics and outlines key obstacles and opportunit...

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Bibliographic Details
Main Authors:	Ulrik Stervbo, Paraskevas Filippidis, Felix Breden, Lindsay G. Cowell, Frederic Davi, Victor Greiff, Anton W. Langerak, Eline T. Luning Prak, Alexandra F. Sharland, Enkelejda Miho, Pieter Meysman
Format:	Article
Language:	English
Published:	Elsevier 2025-09-01
Series:	ImmunoInformatics
Subjects:	AIRR-seq Diagnostics Standardization Clinical translation Machine learning Interpretability
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667119025000096
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