Unraveling the enigma of sclerosing encapsulating peritonitis: a comprehensive review
Sclerosing encapsulating peritonitis (SEP) is a rare but serious condition characterized by the progressive formation of a dense fibrous sheath encasing the small bowel within the peritoneal cavity. This review provides a comprehensive overview of the current understanding of SEP, focusing on its et...
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| Format: | Article |
| Language: | English |
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Korean Society of Coloproctology
2025-06-01
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| Series: | Annals of Coloproctology |
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| Online Access: | http://coloproctol.org/upload/pdf/ac-2024-00486-0069.pdf |
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| author | Witcha Vipudhamorn Tawan Juthasilaparut Pawit Sutharat Suwan Sanmee Ekkarin Supatrakul Sayanan Chowsilpa Kraipop Wongwaiyut Rujee Rattanasathien |
| author_facet | Witcha Vipudhamorn Tawan Juthasilaparut Pawit Sutharat Suwan Sanmee Ekkarin Supatrakul Sayanan Chowsilpa Kraipop Wongwaiyut Rujee Rattanasathien |
| author_sort | Witcha Vipudhamorn |
| collection | DOAJ |
| description | Sclerosing encapsulating peritonitis (SEP) is a rare but serious condition characterized by the progressive formation of a dense fibrous sheath encasing the small bowel within the peritoneal cavity. This review provides a comprehensive overview of the current understanding of SEP, focusing on its etiology, clinical presentation, diagnostic modalities, and management strategies. SEP can be classified into primary and secondary forms, each with distinct etiologies and treatment approaches. Primary SEP typically presents with acute or subacute bowel obstruction symptoms, necessitating surgical intervention to excise the fibrous sheath and relieve the obstruction. Secondary SEP often occurs in patients undergoing peritoneal dialysis, with cessation of dialysis being a key component of management. Medical treatments, including corticosteroids, immunosuppressive agents, and nutritional support, may complement surgical intervention, particularly in cases of secondary SEP. Advanced imaging techniques and personalized medicine approaches show promise in improving diagnostic accuracy and tailoring treatment strategies to individual patients. Future research directions include investigating targeted pharmacological therapies, exploring minimally invasive surgical techniques, and conducting long-term follow-up studies to evaluate treatment efficacy and disease recurrence. Multidisciplinary care teams play a crucial role in the comprehensive management of SEP, emphasizing collaboration among various specialties to optimize patient outcomes. |
| format | Article |
| id | doaj-art-d5dec75c4cd346308cc4da45c52caa06 |
| institution | Kabale University |
| issn | 2287-9714 2287-9722 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Korean Society of Coloproctology |
| record_format | Article |
| series | Annals of Coloproctology |
| spelling | doaj-art-d5dec75c4cd346308cc4da45c52caa062025-08-20T03:29:19ZengKorean Society of ColoproctologyAnnals of Coloproctology2287-97142287-97222025-06-0141317518910.3393/ac.2024.00486.00692086Unraveling the enigma of sclerosing encapsulating peritonitis: a comprehensive reviewWitcha Vipudhamorn0Tawan Juthasilaparut1Pawit Sutharat2Suwan Sanmee3Ekkarin Supatrakul4Sayanan Chowsilpa5Kraipop Wongwaiyut6Rujee Rattanasathien7 Division of Colorectal Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Department of Surgery, Lampang Hospital, Lampang, Thailand Division of Colorectal Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Division of Colorectal Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Division of Colorectal Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Department of Surgery, Trang Hospital, Trang, Thailand Clinical Surgical Research Center, Chiang Mai University, Chiang Mai, ThailandSclerosing encapsulating peritonitis (SEP) is a rare but serious condition characterized by the progressive formation of a dense fibrous sheath encasing the small bowel within the peritoneal cavity. This review provides a comprehensive overview of the current understanding of SEP, focusing on its etiology, clinical presentation, diagnostic modalities, and management strategies. SEP can be classified into primary and secondary forms, each with distinct etiologies and treatment approaches. Primary SEP typically presents with acute or subacute bowel obstruction symptoms, necessitating surgical intervention to excise the fibrous sheath and relieve the obstruction. Secondary SEP often occurs in patients undergoing peritoneal dialysis, with cessation of dialysis being a key component of management. Medical treatments, including corticosteroids, immunosuppressive agents, and nutritional support, may complement surgical intervention, particularly in cases of secondary SEP. Advanced imaging techniques and personalized medicine approaches show promise in improving diagnostic accuracy and tailoring treatment strategies to individual patients. Future research directions include investigating targeted pharmacological therapies, exploring minimally invasive surgical techniques, and conducting long-term follow-up studies to evaluate treatment efficacy and disease recurrence. Multidisciplinary care teams play a crucial role in the comprehensive management of SEP, emphasizing collaboration among various specialties to optimize patient outcomes.http://coloproctol.org/upload/pdf/ac-2024-00486-0069.pdfperitoneal fibrosisabdominal cocoonperitoneal dialysisperitoneal diseasesimmunosuppressive agents |
| spellingShingle | Witcha Vipudhamorn Tawan Juthasilaparut Pawit Sutharat Suwan Sanmee Ekkarin Supatrakul Sayanan Chowsilpa Kraipop Wongwaiyut Rujee Rattanasathien Unraveling the enigma of sclerosing encapsulating peritonitis: a comprehensive review Annals of Coloproctology peritoneal fibrosis abdominal cocoon peritoneal dialysis peritoneal diseases immunosuppressive agents |
| title | Unraveling the enigma of sclerosing encapsulating peritonitis: a comprehensive review |
| title_full | Unraveling the enigma of sclerosing encapsulating peritonitis: a comprehensive review |
| title_fullStr | Unraveling the enigma of sclerosing encapsulating peritonitis: a comprehensive review |
| title_full_unstemmed | Unraveling the enigma of sclerosing encapsulating peritonitis: a comprehensive review |
| title_short | Unraveling the enigma of sclerosing encapsulating peritonitis: a comprehensive review |
| title_sort | unraveling the enigma of sclerosing encapsulating peritonitis a comprehensive review |
| topic | peritoneal fibrosis abdominal cocoon peritoneal dialysis peritoneal diseases immunosuppressive agents |
| url | http://coloproctol.org/upload/pdf/ac-2024-00486-0069.pdf |
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