Analysis on the application of a CT-guided medical adhesive-based localization method in sublobectomy to ensure surgical margins
Abstract Background Sublobectomy is one of the standard surgical procedures for early stage lung cancer. The distance of resection margin is the basic demand of sublobectomy. Therefore, it is of great clinical significance to ensure the margin distance in sublobectomy. How to ensure the margin dista...
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BMC
2025-07-01
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| Series: | BMC Pulmonary Medicine |
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| Online Access: | https://doi.org/10.1186/s12890-025-03762-2 |
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| author | Shanhai Yu Xianling Duan Jungang Ma Wei Li Nianxin Zhang Xiangding Liu Zhizhong Yan Yuyin Zhang Lixiang Wang Liwei Zhang |
| author_facet | Shanhai Yu Xianling Duan Jungang Ma Wei Li Nianxin Zhang Xiangding Liu Zhizhong Yan Yuyin Zhang Lixiang Wang Liwei Zhang |
| author_sort | Shanhai Yu |
| collection | DOAJ |
| description | Abstract Background Sublobectomy is one of the standard surgical procedures for early stage lung cancer. The distance of resection margin is the basic demand of sublobectomy. Therefore, it is of great clinical significance to ensure the margin distance in sublobectomy. How to ensure the margin distance in sublobectomy is still a difficult problem for thoracic surgeons. Our center has recently adopted the CT-guided medical adhesive localization method to solve the problem of insufficient lung margins with excellent results. Methods The clinical data of 40 patients with pulmonary nodules, who received VATS-based sublobectomy during the period from January 2022 to February 2023 in the Department of Thoracic Surgery, Juxian People’s Hospital, Shandong Province, were retrospectively analyzed. All the patients underwent CT-guided lung puncture for medical adhesive-based pulmonary nodule localization before surgery. After resection, the distance between the pulmonary nodule and the surgical margin was measured, and the surgical margin was routinely sent for examination. The clinical case data of the patients were collected. Results All the 40 patients in the group successfully underwent percutaneous lung puncture for medical adhesive-based localization under local anesthesia. For all the patients, the distance between the lesion and the surgical margin was greater than 2 cm, and the surgical margin tested negative, with a localization success rate of 100%, and a localization duration of (15.0 ± 3.6) min. Localization complications included 2 cases of slight pneumothorax, 2 cases of bleeding along the needle tract, and 1 case of hemoptysis, none of which required special treatment. Conclusion CT-guided medical adhesive-based localization is a safe, effective and simple localization method, which has important clinical application value in ensuring the safety of surgical margins of pulmonary nodules and reducing the time needed to locate lesions during surgery. |
| format | Article |
| id | doaj-art-d5d94ce408084ee1bfa883937f8ebae0 |
| institution | DOAJ |
| issn | 1471-2466 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj-art-d5d94ce408084ee1bfa883937f8ebae02025-08-20T03:03:23ZengBMCBMC Pulmonary Medicine1471-24662025-07-012511610.1186/s12890-025-03762-2Analysis on the application of a CT-guided medical adhesive-based localization method in sublobectomy to ensure surgical marginsShanhai Yu0Xianling Duan1Jungang Ma2Wei Li3Nianxin Zhang4Xiangding Liu5Zhizhong Yan6Yuyin Zhang7Lixiang Wang8Liwei Zhang9Department of Thoracic Surgery, Juxian People’s HospitalOperating Room, Juxian People’s HospitalPulmonary and Critial Care Medicine, Juxian People’s HospitalDepartment of Thoracic Surgery, Juxian People’s HospitalDepartment of Thoracic Surgery, Juxian People’s HospitalDepartment of Thoracic Surgery, Juxian People’s HospitalDepartment of Thoracic Surgery, Juxian People’s HospitalDepartment of Thoracic Surgery, Juxian People’s HospitalDepartment of Thoracic Surgery, Juxian People’s HospitalDepartment of Thoracic Surgery, The First Affiliated Hospital of Xinjiang Medical UniversityAbstract Background Sublobectomy is one of the standard surgical procedures for early stage lung cancer. The distance of resection margin is the basic demand of sublobectomy. Therefore, it is of great clinical significance to ensure the margin distance in sublobectomy. How to ensure the margin distance in sublobectomy is still a difficult problem for thoracic surgeons. Our center has recently adopted the CT-guided medical adhesive localization method to solve the problem of insufficient lung margins with excellent results. Methods The clinical data of 40 patients with pulmonary nodules, who received VATS-based sublobectomy during the period from January 2022 to February 2023 in the Department of Thoracic Surgery, Juxian People’s Hospital, Shandong Province, were retrospectively analyzed. All the patients underwent CT-guided lung puncture for medical adhesive-based pulmonary nodule localization before surgery. After resection, the distance between the pulmonary nodule and the surgical margin was measured, and the surgical margin was routinely sent for examination. The clinical case data of the patients were collected. Results All the 40 patients in the group successfully underwent percutaneous lung puncture for medical adhesive-based localization under local anesthesia. For all the patients, the distance between the lesion and the surgical margin was greater than 2 cm, and the surgical margin tested negative, with a localization success rate of 100%, and a localization duration of (15.0 ± 3.6) min. Localization complications included 2 cases of slight pneumothorax, 2 cases of bleeding along the needle tract, and 1 case of hemoptysis, none of which required special treatment. Conclusion CT-guided medical adhesive-based localization is a safe, effective and simple localization method, which has important clinical application value in ensuring the safety of surgical margins of pulmonary nodules and reducing the time needed to locate lesions during surgery.https://doi.org/10.1186/s12890-025-03762-2Surgical marginMedical adhesiveIntraoperative localizationPulmonary ground-glass noduleSublobectomy |
| spellingShingle | Shanhai Yu Xianling Duan Jungang Ma Wei Li Nianxin Zhang Xiangding Liu Zhizhong Yan Yuyin Zhang Lixiang Wang Liwei Zhang Analysis on the application of a CT-guided medical adhesive-based localization method in sublobectomy to ensure surgical margins BMC Pulmonary Medicine Surgical margin Medical adhesive Intraoperative localization Pulmonary ground-glass nodule Sublobectomy |
| title | Analysis on the application of a CT-guided medical adhesive-based localization method in sublobectomy to ensure surgical margins |
| title_full | Analysis on the application of a CT-guided medical adhesive-based localization method in sublobectomy to ensure surgical margins |
| title_fullStr | Analysis on the application of a CT-guided medical adhesive-based localization method in sublobectomy to ensure surgical margins |
| title_full_unstemmed | Analysis on the application of a CT-guided medical adhesive-based localization method in sublobectomy to ensure surgical margins |
| title_short | Analysis on the application of a CT-guided medical adhesive-based localization method in sublobectomy to ensure surgical margins |
| title_sort | analysis on the application of a ct guided medical adhesive based localization method in sublobectomy to ensure surgical margins |
| topic | Surgical margin Medical adhesive Intraoperative localization Pulmonary ground-glass nodule Sublobectomy |
| url | https://doi.org/10.1186/s12890-025-03762-2 |
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