Cognitive Impairment Associated with Schizophrenia: A Case Report
Introduction: First-generation antipsychotics could reduce the positive symptoms of schizophrenia but also impair cognitive function. Cognitive and negative symptoms in schizophrenia could be a significant burden experienced both by the patients and caregivers. Thus the treatment of cognitive impair...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2025-05-01
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| Series: | Jurnal Psikiatri Surabaya |
| Online Access: | https://e-journal.unair.ac.id/JPS/article/view/49488 |
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| author | Lia Jessica Yulia Fatima Bessing Erikavitri Yulianti Salma Nur Fadhilah |
| author_facet | Lia Jessica Yulia Fatima Bessing Erikavitri Yulianti Salma Nur Fadhilah |
| author_sort | Lia Jessica |
| collection | DOAJ |
| description | Introduction: First-generation antipsychotics could reduce the positive symptoms of schizophrenia but also impair cognitive function. Cognitive and negative symptoms in schizophrenia could be a significant burden experienced both by the patients and caregivers. Thus the treatment of cognitive impairment associated with schizophrenia should be addressed properly. The purpose of writing this article is to increase awareness in administering antipsychotics to elderly patients with schizophrenia, especially in the cognitive aspect and how to overcome possible cognitive decline. Case: An outpatient female schizophrenic patient who was on first-generation antipsychotic treatment complained of forgetfulness. The complaint started 5 years after she received her treatment. While she could still perform her activities of daily living independently, her instrumental activities of daily living were impaired. Her food got burnt while she was cooking, and she also took her medicine excessively because she forgot about it. Both of those events could be very dangerous for her. Discussion: Antipsychotics are the first-line pharmacotherapy for the treatment of schizophrenia but could also cause cognitive impairment. Management of cognitive impairment associated with schizophrenia could be performed both non-pharmacologically, by giving cognitive remediation therapy or physical exercise, and pharmacologically, by giving cholinergic agents such as donepezil. Conclusions: Cognitive impairment associated with schizophrenia should be managed as well as psychotic symptoms. |
| format | Article |
| id | doaj-art-d5d54efe151b4f87bc62294c4b01f256 |
| institution | Kabale University |
| issn | 2355-2409 2716-358X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Jurnal Psikiatri Surabaya |
| spelling | doaj-art-d5d54efe151b4f87bc62294c4b01f2562025-08-20T03:52:02ZengUniversitas AirlanggaJurnal Psikiatri Surabaya2355-24092716-358X2025-05-0114112813247635Cognitive Impairment Associated with Schizophrenia: A Case ReportLia Jessica0Yulia Fatima Bessing1Erikavitri Yulianti2https://orcid.org/0009-0005-0798-5580Salma Nur Fadhilah3Department of Psychiatry, Faculty of Medicine, Universitas Airlangga, SurabayaDr. Radjiman Wediodiningrat Psychiatric Hospital, LawangDepartment of Psychiatry, Faculty of Medicine, Universitas Airlangga, SurabayaMSc Developmental Psychology & Psychopathology Student, King's College London, LondonIntroduction: First-generation antipsychotics could reduce the positive symptoms of schizophrenia but also impair cognitive function. Cognitive and negative symptoms in schizophrenia could be a significant burden experienced both by the patients and caregivers. Thus the treatment of cognitive impairment associated with schizophrenia should be addressed properly. The purpose of writing this article is to increase awareness in administering antipsychotics to elderly patients with schizophrenia, especially in the cognitive aspect and how to overcome possible cognitive decline. Case: An outpatient female schizophrenic patient who was on first-generation antipsychotic treatment complained of forgetfulness. The complaint started 5 years after she received her treatment. While she could still perform her activities of daily living independently, her instrumental activities of daily living were impaired. Her food got burnt while she was cooking, and she also took her medicine excessively because she forgot about it. Both of those events could be very dangerous for her. Discussion: Antipsychotics are the first-line pharmacotherapy for the treatment of schizophrenia but could also cause cognitive impairment. Management of cognitive impairment associated with schizophrenia could be performed both non-pharmacologically, by giving cognitive remediation therapy or physical exercise, and pharmacologically, by giving cholinergic agents such as donepezil. Conclusions: Cognitive impairment associated with schizophrenia should be managed as well as psychotic symptoms.https://e-journal.unair.ac.id/JPS/article/view/49488 |
| spellingShingle | Lia Jessica Yulia Fatima Bessing Erikavitri Yulianti Salma Nur Fadhilah Cognitive Impairment Associated with Schizophrenia: A Case Report Jurnal Psikiatri Surabaya |
| title | Cognitive Impairment Associated with Schizophrenia: A Case Report |
| title_full | Cognitive Impairment Associated with Schizophrenia: A Case Report |
| title_fullStr | Cognitive Impairment Associated with Schizophrenia: A Case Report |
| title_full_unstemmed | Cognitive Impairment Associated with Schizophrenia: A Case Report |
| title_short | Cognitive Impairment Associated with Schizophrenia: A Case Report |
| title_sort | cognitive impairment associated with schizophrenia a case report |
| url | https://e-journal.unair.ac.id/JPS/article/view/49488 |
| work_keys_str_mv | AT liajessica cognitiveimpairmentassociatedwithschizophreniaacasereport AT yuliafatimabessing cognitiveimpairmentassociatedwithschizophreniaacasereport AT erikavitriyulianti cognitiveimpairmentassociatedwithschizophreniaacasereport AT salmanurfadhilah cognitiveimpairmentassociatedwithschizophreniaacasereport |