Prevalence of low back pain in hemodialysis patients: A systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation evidence classification

Background: Musculoskeletal pain complaints have a high epidemiological and clinical burden in hemodialysis patients. Previous original studies indicate that low back pain (LBP) may have an important contribution to these complaints. This systematic review aimed to estimate the global prevalence of...

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Main Authors: Marcospaulo Viana Milagres, Juliano Bergamaschine Mata Diz, Alfredo Chaoubah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Craniovertebral Junction and Spine
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Online Access:https://journals.lww.com/10.4103/jcvjs.jcvjs_192_24
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author Marcospaulo Viana Milagres
Juliano Bergamaschine Mata Diz
Alfredo Chaoubah
author_facet Marcospaulo Viana Milagres
Juliano Bergamaschine Mata Diz
Alfredo Chaoubah
author_sort Marcospaulo Viana Milagres
collection DOAJ
description Background: Musculoskeletal pain complaints have a high epidemiological and clinical burden in hemodialysis patients. Previous original studies indicate that low back pain (LBP) may have an important contribution to these complaints. This systematic review aimed to estimate the global prevalence of LBP in chronic hemodialysis patients. Methods: Systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation approach for quality of evidence. Searches were performed in CINAHL, Embase, LILACS, MEDLINE/PubMed, and Scientific Electronic Library Online databases until July 2023. The Inverse Variance Heterogeneity model was used to pool prevalence estimates. Results: The review included 19 original articles that provided data from 2713 patients. The overall pooled prevalence of LBP was 30.2% (95% confidence interval [CI] =19.0%–42.0%; k = 19 articles). The sex-specific pooled prevalence of LBP was 29.6% (95% CI = 18.7%–41.2%; k = 6 articles) in females and 36.6% (95% CI = 26.0%–47.7%; k = 6 articles) in males. The duration-specific pooled prevalence of LBP was 13.2% (95% CI = 8.6%–18.4%; k = 2 articles) for acute and 30.7% (95% CI = 11.3%–52.2%; k = 7 articles) for chronic LBP. The frequency of LBP estimated over the total number of pain complaints was 39.6% (95% CI = 23.0%–56.8%; k = 10 articles). Conclusion: The overall estimate shows that three out of 10 hemodialysis patients suffer from LBP. This condition is accountable for nearly 40% of pain complaints in such patients. The quality of evidence for the pooled estimates is low or very low, and future prevalence studies with adequate statistical power and definitions of LBP are needed to provide more accurate data.
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spelling doaj-art-d5d53e760ca949879245f00624b5cb5c2025-08-20T03:24:43ZengWolters Kluwer Medknow PublicationsJournal of Craniovertebral Junction and Spine0974-82370976-92852025-01-01161162510.4103/jcvjs.jcvjs_192_24Prevalence of low back pain in hemodialysis patients: A systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation evidence classificationMarcospaulo Viana MilagresJuliano Bergamaschine Mata DizAlfredo ChaoubahBackground: Musculoskeletal pain complaints have a high epidemiological and clinical burden in hemodialysis patients. Previous original studies indicate that low back pain (LBP) may have an important contribution to these complaints. This systematic review aimed to estimate the global prevalence of LBP in chronic hemodialysis patients. Methods: Systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation approach for quality of evidence. Searches were performed in CINAHL, Embase, LILACS, MEDLINE/PubMed, and Scientific Electronic Library Online databases until July 2023. The Inverse Variance Heterogeneity model was used to pool prevalence estimates. Results: The review included 19 original articles that provided data from 2713 patients. The overall pooled prevalence of LBP was 30.2% (95% confidence interval [CI] =19.0%–42.0%; k = 19 articles). The sex-specific pooled prevalence of LBP was 29.6% (95% CI = 18.7%–41.2%; k = 6 articles) in females and 36.6% (95% CI = 26.0%–47.7%; k = 6 articles) in males. The duration-specific pooled prevalence of LBP was 13.2% (95% CI = 8.6%–18.4%; k = 2 articles) for acute and 30.7% (95% CI = 11.3%–52.2%; k = 7 articles) for chronic LBP. The frequency of LBP estimated over the total number of pain complaints was 39.6% (95% CI = 23.0%–56.8%; k = 10 articles). Conclusion: The overall estimate shows that three out of 10 hemodialysis patients suffer from LBP. This condition is accountable for nearly 40% of pain complaints in such patients. The quality of evidence for the pooled estimates is low or very low, and future prevalence studies with adequate statistical power and definitions of LBP are needed to provide more accurate data.https://journals.lww.com/10.4103/jcvjs.jcvjs_192_24grading of recommendations assessmentdevelopmentand evaluation approachlow back painprevalencerenal dialysissystematic review
spellingShingle Marcospaulo Viana Milagres
Juliano Bergamaschine Mata Diz
Alfredo Chaoubah
Prevalence of low back pain in hemodialysis patients: A systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation evidence classification
Journal of Craniovertebral Junction and Spine
grading of recommendations assessment
development
and evaluation approach
low back pain
prevalence
renal dialysis
systematic review
title Prevalence of low back pain in hemodialysis patients: A systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation evidence classification
title_full Prevalence of low back pain in hemodialysis patients: A systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation evidence classification
title_fullStr Prevalence of low back pain in hemodialysis patients: A systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation evidence classification
title_full_unstemmed Prevalence of low back pain in hemodialysis patients: A systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation evidence classification
title_short Prevalence of low back pain in hemodialysis patients: A systematic review and meta-analysis with Grading of Recommendations Assessment, Development, and Evaluation evidence classification
title_sort prevalence of low back pain in hemodialysis patients a systematic review and meta analysis with grading of recommendations assessment development and evaluation evidence classification
topic grading of recommendations assessment
development
and evaluation approach
low back pain
prevalence
renal dialysis
systematic review
url https://journals.lww.com/10.4103/jcvjs.jcvjs_192_24
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