Analysis of efficacy of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on disease activity

The objective: to study the frequency of post-operative complications and outcomes of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on the activity of tuberculous inflammation.Subjects and methods. 722 patients were enrolled into the study, they all un...

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Main Authors: D. E. Omelchuk, D. V. Krasnov, Т. I. Petrenko, I. A. Bolshakova
Format: Article
Language:Russian
Published: New Terra Publishing House 2019-09-01
Series:Туберкулез и болезни лёгких
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Online Access:https://www.tibl-journal.com/jour/article/view/1321
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author D. E. Omelchuk
D. V. Krasnov
Т. I. Petrenko
I. A. Bolshakova
author_facet D. E. Omelchuk
D. V. Krasnov
Т. I. Petrenko
I. A. Bolshakova
author_sort D. E. Omelchuk
collection DOAJ
description The objective: to study the frequency of post-operative complications and outcomes of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on the activity of tuberculous inflammation.Subjects and methods. 722 patients were enrolled into the study, they all underwent radical surgery for fibrous cavernous pulmonary tuberculosis in the Krasnoyarsk Regional TB Dispensary No. 1. In all cases, the diagnosis of fibrous cavernous tuberculosis was confirmed by pathomorphological tests after surgery. The severity of tuberculous inflammation was evaluated based on the following generally available indicators: massivity of bacterial excretion, erythrocyte sedimentation rate, x-ray changes over 2 months before the surgery. Depending on the activity of the disease, patients were divided into three groups: those with low activity (479 patients), medium activity (171 patients) and high activity (72 patients).Results. The outcome of resection surgery due to fibrous cavernous pulmonary tuberculosis performed in patients with low tuberculosis activity was more favorable compared to moderate and high exacerbation activity and especially pronounced exacerbation, as indicated by the achievement of a complete clinical effect in 92.7, 74.3, and 37.5%, respectively, and a more favorable course of the postoperative period. Thus, the frequency of severe postoperative complications made in 12.1, 26.3, and 55.6% of patients, respectively. This situation was also confirmed in operations of the same type (among patients with pneumonectomy and among patients with lung resection). The high activity of tuberculosis should be considered a relative contraindication to surgical resections.
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series Туберкулез и болезни лёгких
spelling doaj-art-d5d38223ed064c9da98c7b752c4dfcf22025-08-20T02:05:49ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-09-01978222610.21292/2075-1230-2019-97-8-22-261321Analysis of efficacy of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on disease activityD. E. Omelchuk0D. V. Krasnov1Т. I. Petrenko2I. A. Bolshakova3V. F. Voyno-Yasenetsky State Medical University, Russian Ministry of Health; Krasnoyarsk Regional TB Dispensary no. 1Novosibirsk Tuberculosis Research Institute; Novosibirsk State Medical UniversityNovosibirsk Tuberculosis Research Institute; Novosibirsk State Medical UniversityV. F. Voyno-Yasenetsky State Medical University, Russian Ministry of HealthThe objective: to study the frequency of post-operative complications and outcomes of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on the activity of tuberculous inflammation.Subjects and methods. 722 patients were enrolled into the study, they all underwent radical surgery for fibrous cavernous pulmonary tuberculosis in the Krasnoyarsk Regional TB Dispensary No. 1. In all cases, the diagnosis of fibrous cavernous tuberculosis was confirmed by pathomorphological tests after surgery. The severity of tuberculous inflammation was evaluated based on the following generally available indicators: massivity of bacterial excretion, erythrocyte sedimentation rate, x-ray changes over 2 months before the surgery. Depending on the activity of the disease, patients were divided into three groups: those with low activity (479 patients), medium activity (171 patients) and high activity (72 patients).Results. The outcome of resection surgery due to fibrous cavernous pulmonary tuberculosis performed in patients with low tuberculosis activity was more favorable compared to moderate and high exacerbation activity and especially pronounced exacerbation, as indicated by the achievement of a complete clinical effect in 92.7, 74.3, and 37.5%, respectively, and a more favorable course of the postoperative period. Thus, the frequency of severe postoperative complications made in 12.1, 26.3, and 55.6% of patients, respectively. This situation was also confirmed in operations of the same type (among patients with pneumonectomy and among patients with lung resection). The high activity of tuberculosis should be considered a relative contraindication to surgical resections.https://www.tibl-journal.com/jour/article/view/1321surgical treatmentlung resectionpulmonary fibrous cavernous tuberculosis
spellingShingle D. E. Omelchuk
D. V. Krasnov
Т. I. Petrenko
I. A. Bolshakova
Analysis of efficacy of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on disease activity
Туберкулез и болезни лёгких
surgical treatment
lung resection
pulmonary fibrous cavernous tuberculosis
title Analysis of efficacy of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on disease activity
title_full Analysis of efficacy of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on disease activity
title_fullStr Analysis of efficacy of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on disease activity
title_full_unstemmed Analysis of efficacy of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on disease activity
title_short Analysis of efficacy of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on disease activity
title_sort analysis of efficacy of lung resections and pneumonectomies in patients with fibrous cavernous tuberculosis depending on disease activity
topic surgical treatment
lung resection
pulmonary fibrous cavernous tuberculosis
url https://www.tibl-journal.com/jour/article/view/1321
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AT tipetrenko analysisofefficacyoflungresectionsandpneumonectomiesinpatientswithfibrouscavernoustuberculosisdependingondiseaseactivity
AT iabolshakova analysisofefficacyoflungresectionsandpneumonectomiesinpatientswithfibrouscavernoustuberculosisdependingondiseaseactivity