The effects of early nutritional contents in premature infants on the development and severity of retinopathy: A retrospective case-control study
Objectives: Poor weight gain during the first weeks of life in preterm infants is associated with the risk of developing retinopathy of prematurity (ROP). Our study aimed to evaluate the effect of energy, macronutrient intake, and weight gain during the first 4 weeks of life on the risk of ROP. M...
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Aydın Pediatric Society
2023-12-01
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| Series: | Trends in Pediatrics |
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| Online Access: | https://trendspediatrics.com/article/view/108 |
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| author | Mustafa Şenol Akın Şule Yiğit |
| author_facet | Mustafa Şenol Akın Şule Yiğit |
| author_sort | Mustafa Şenol Akın |
| collection | DOAJ |
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Objectives: Poor weight gain during the first weeks of life in preterm infants is associated with the risk of developing retinopathy of prematurity (ROP). Our study aimed to evaluate the effect of energy, macronutrient intake, and weight gain during the first 4 weeks of life on the risk of ROP.
Methods: This study was designed as a single-center, retrospective, and case-control trial. Premature babies, born before the 30th week of gestation, were included in our study. The infants were divided into three groups: control (without ROP), mild ROP, and severe ROP groups. Possible nutritional risk factors for ROP were compared.
Results: ROP was found in 32 (29.5%) of 108 infants included in this study. The first enteral feeding day, full enteral feeding day, and total duration of parenteral nutrition were significantly higher in infants with level 3-4 ROP than the others (p <0.05). The risk of severe ROP increased in infants who gained less than 8 g/day and who received less than 91 kcal/kg of calories (p <0.05). It was found that infants with severe ROP received statistically (p <0.05) less breast milk, but there was no difference in formula intake (p >0.05).
Conclusions: We showed that low energy intake during the first 4 weeks of life is an independent risk factor for severe ROP. This implies that the provision of adequate energy from parenteral and enteral sources during the first 4 weeks of life may be an effective method to reduce the risk of severe ROP in preterm infants.
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| format | Article |
| id | doaj-art-d5bcc0a873884ee791ad1b72e4a839b2 |
| institution | DOAJ |
| issn | 2792-0429 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Aydın Pediatric Society |
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| series | Trends in Pediatrics |
| spelling | doaj-art-d5bcc0a873884ee791ad1b72e4a839b22025-08-20T02:45:31ZengAydın Pediatric SocietyTrends in Pediatrics2792-04292023-12-014410.59213/TP.2023.68442The effects of early nutritional contents in premature infants on the development and severity of retinopathy: A retrospective case-control studyMustafa Şenol Akın0https://orcid.org/0000-0003-0055-8277Şule Yiğit1https://orcid.org/0000-0002-8755-0384Department of Pediatrics, Division of Neonatology, Ankara Bilkent City Hospital, Ankara, TürkiyeDepartment of Pediatrics, Division of Neonatology, Hacettepe University, Ankara, Türkiye Objectives: Poor weight gain during the first weeks of life in preterm infants is associated with the risk of developing retinopathy of prematurity (ROP). Our study aimed to evaluate the effect of energy, macronutrient intake, and weight gain during the first 4 weeks of life on the risk of ROP. Methods: This study was designed as a single-center, retrospective, and case-control trial. Premature babies, born before the 30th week of gestation, were included in our study. The infants were divided into three groups: control (without ROP), mild ROP, and severe ROP groups. Possible nutritional risk factors for ROP were compared. Results: ROP was found in 32 (29.5%) of 108 infants included in this study. The first enteral feeding day, full enteral feeding day, and total duration of parenteral nutrition were significantly higher in infants with level 3-4 ROP than the others (p <0.05). The risk of severe ROP increased in infants who gained less than 8 g/day and who received less than 91 kcal/kg of calories (p <0.05). It was found that infants with severe ROP received statistically (p <0.05) less breast milk, but there was no difference in formula intake (p >0.05). Conclusions: We showed that low energy intake during the first 4 weeks of life is an independent risk factor for severe ROP. This implies that the provision of adequate energy from parenteral and enteral sources during the first 4 weeks of life may be an effective method to reduce the risk of severe ROP in preterm infants. https://trendspediatrics.com/article/view/108Retinopathy of prematuritytotal parenteral nutritionweight gainpremature |
| spellingShingle | Mustafa Şenol Akın Şule Yiğit The effects of early nutritional contents in premature infants on the development and severity of retinopathy: A retrospective case-control study Trends in Pediatrics Retinopathy of prematurity total parenteral nutrition weight gain premature |
| title | The effects of early nutritional contents in premature infants on the development and severity of retinopathy: A retrospective case-control study |
| title_full | The effects of early nutritional contents in premature infants on the development and severity of retinopathy: A retrospective case-control study |
| title_fullStr | The effects of early nutritional contents in premature infants on the development and severity of retinopathy: A retrospective case-control study |
| title_full_unstemmed | The effects of early nutritional contents in premature infants on the development and severity of retinopathy: A retrospective case-control study |
| title_short | The effects of early nutritional contents in premature infants on the development and severity of retinopathy: A retrospective case-control study |
| title_sort | effects of early nutritional contents in premature infants on the development and severity of retinopathy a retrospective case control study |
| topic | Retinopathy of prematurity total parenteral nutrition weight gain premature |
| url | https://trendspediatrics.com/article/view/108 |
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