Parameter Optimization, Morphological and Histological Characteristics of Accurate Bone Ablation by Femtosecond Laser: An In Vitro Study
The use of femtosecond laser for bone ablation has been demonstrated in numerous studies; however, the clinical application requires further optimization to meet safety, accuracy, and efficiency standards. This study aims to optimize the energy density parameter of a robot-controlled femtosecond las...
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MDPI AG
2025-02-01
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| Series: | Bioengineering |
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| author | Yiyang Wang Shanshan Liang Yongsheng Zhou Fusong Yuan Hongqiang Ye |
| author_facet | Yiyang Wang Shanshan Liang Yongsheng Zhou Fusong Yuan Hongqiang Ye |
| author_sort | Yiyang Wang |
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| description | The use of femtosecond laser for bone ablation has been demonstrated in numerous studies; however, the clinical application requires further optimization to meet safety, accuracy, and efficiency standards. This study aims to optimize the energy density parameter of a robot-controlled femtosecond laser surgical system for bone ablation by assessing temperature changes, ablation efficiency, and ablation effects. Furthermore, the morphological and histological characteristics of bone tissue were compared with those of conventional mechanical methods. The results indicated that a laser energy density of 1.05 J/cm<sup>2</sup> was optimal for bone ablation, maintaining the bone surface temperature below 47 °C and achieving an ablation efficiency of 0.145 mm<sup>3</sup>/s. The deviations in cavity diameters were significantly smaller for the laser group (6.58 ± 18.09 μm) compared to the bur group (80.09 ± 45.45 μm, <i>p</i> < 0.001, <i>N</i> = 5 per group). Femtosecond laser ablation produced cleaner cavity margins with minimal bone debris accumulation. Additionally, the adjacent Volkmann and Haversian canals retained their normal morphology, indicating limited mechanical and thermal damage to the bone tissue. The robot-controlled femtosecond laser system demonstrated the potential for achieving safe, accurate, efficient, and clean bone ablation, offering promising prospects for clinical applications. |
| format | Article |
| id | doaj-art-d5bc0477cce14c3e8f3efe836cf3bd15 |
| institution | Kabale University |
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| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
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| series | Bioengineering |
| spelling | doaj-art-d5bc0477cce14c3e8f3efe836cf3bd152025-08-20T03:43:21ZengMDPI AGBioengineering2306-53542025-02-0112321710.3390/bioengineering12030217Parameter Optimization, Morphological and Histological Characteristics of Accurate Bone Ablation by Femtosecond Laser: An In Vitro StudyYiyang Wang0Shanshan Liang1Yongsheng Zhou2Fusong Yuan3Hongqiang Ye4Department of Prosthodontics, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaCenter of Digital Dentistry, Department of Prosthodontics, Second Clinical Division, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, Beijing 100081, ChinaDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaCenter of Digital Dentistry, Department of Prosthodontics, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, Beijing 100081, ChinaDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaThe use of femtosecond laser for bone ablation has been demonstrated in numerous studies; however, the clinical application requires further optimization to meet safety, accuracy, and efficiency standards. This study aims to optimize the energy density parameter of a robot-controlled femtosecond laser surgical system for bone ablation by assessing temperature changes, ablation efficiency, and ablation effects. Furthermore, the morphological and histological characteristics of bone tissue were compared with those of conventional mechanical methods. The results indicated that a laser energy density of 1.05 J/cm<sup>2</sup> was optimal for bone ablation, maintaining the bone surface temperature below 47 °C and achieving an ablation efficiency of 0.145 mm<sup>3</sup>/s. The deviations in cavity diameters were significantly smaller for the laser group (6.58 ± 18.09 μm) compared to the bur group (80.09 ± 45.45 μm, <i>p</i> < 0.001, <i>N</i> = 5 per group). Femtosecond laser ablation produced cleaner cavity margins with minimal bone debris accumulation. Additionally, the adjacent Volkmann and Haversian canals retained their normal morphology, indicating limited mechanical and thermal damage to the bone tissue. The robot-controlled femtosecond laser system demonstrated the potential for achieving safe, accurate, efficient, and clean bone ablation, offering promising prospects for clinical applications.https://www.mdpi.com/2306-5354/12/3/217ultrafast laserfemtosecond laserbone ablationsurgical robotparameter optimizationlaser energy density |
| spellingShingle | Yiyang Wang Shanshan Liang Yongsheng Zhou Fusong Yuan Hongqiang Ye Parameter Optimization, Morphological and Histological Characteristics of Accurate Bone Ablation by Femtosecond Laser: An In Vitro Study Bioengineering ultrafast laser femtosecond laser bone ablation surgical robot parameter optimization laser energy density |
| title | Parameter Optimization, Morphological and Histological Characteristics of Accurate Bone Ablation by Femtosecond Laser: An In Vitro Study |
| title_full | Parameter Optimization, Morphological and Histological Characteristics of Accurate Bone Ablation by Femtosecond Laser: An In Vitro Study |
| title_fullStr | Parameter Optimization, Morphological and Histological Characteristics of Accurate Bone Ablation by Femtosecond Laser: An In Vitro Study |
| title_full_unstemmed | Parameter Optimization, Morphological and Histological Characteristics of Accurate Bone Ablation by Femtosecond Laser: An In Vitro Study |
| title_short | Parameter Optimization, Morphological and Histological Characteristics of Accurate Bone Ablation by Femtosecond Laser: An In Vitro Study |
| title_sort | parameter optimization morphological and histological characteristics of accurate bone ablation by femtosecond laser an in vitro study |
| topic | ultrafast laser femtosecond laser bone ablation surgical robot parameter optimization laser energy density |
| url | https://www.mdpi.com/2306-5354/12/3/217 |
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