A Novel Strain of <i>Orientia tsutsugamushi</i> Detected from Chiggers (Acari: Trombiculidae) on Wild Rodents
Scrub typhus is caused by intracellular bacteria belonging to the genus <i>Orientia</i>. Until 2010, the endemic region was thought to be restricted to the Asia–Pacific region. <i>Orientia</i> species have recently been discovered in South America, Africa, Europe, and North A...
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2025-01-01
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| author | Hak Seon Lee Seong Yoon Kim Hee Il Lee |
| author_facet | Hak Seon Lee Seong Yoon Kim Hee Il Lee |
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| description | Scrub typhus is caused by intracellular bacteria belonging to the genus <i>Orientia</i>. Until 2010, the endemic region was thought to be restricted to the Asia–Pacific region. <i>Orientia</i> species have recently been discovered in South America, Africa, Europe, and North America. In accordance with these circumstances, we tried to find new or novel bacterial strains in the Republic of Korea (ROK). We found that a new strain of <i>O. tsutsugamushi</i> formed a unique clade based on a 56-kDa type-specific antigen gene and showed 63.2–77.8% similarity to other strains of the same species. Additionally, we identified another sequence with 99.8% similarity to the O3 strain, which has not been recorded in the ROK and whose pathogenicity remains unknown. These findings confirm the diversity of <i>O. tsutsugamushi</i> strains in the ROK, and highlight the need for continued surveillance and further studies to characterize the pathogenicity of this novel bacterial strain. |
| format | Article |
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| institution | Kabale University |
| issn | 2076-0817 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
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| series | Pathogens |
| spelling | doaj-art-d5b2496b20764a968825151468bac48a2025-01-24T13:44:39ZengMDPI AGPathogens2076-08172025-01-011412910.3390/pathogens14010029A Novel Strain of <i>Orientia tsutsugamushi</i> Detected from Chiggers (Acari: Trombiculidae) on Wild RodentsHak Seon Lee0Seong Yoon Kim1Hee Il Lee2Division of Vectors and Parasitic Diseases, Korea Disease Control and Prevention Agency, 187 Osongsaengmyeong 2-ro, Osong-eup, Heungdeok-gu, Cheongju 28159, Chungbuk, Republic of KoreaDivision of Vectors and Parasitic Diseases, Korea Disease Control and Prevention Agency, 187 Osongsaengmyeong 2-ro, Osong-eup, Heungdeok-gu, Cheongju 28159, Chungbuk, Republic of KoreaDivision of Vectors and Parasitic Diseases, Korea Disease Control and Prevention Agency, 187 Osongsaengmyeong 2-ro, Osong-eup, Heungdeok-gu, Cheongju 28159, Chungbuk, Republic of KoreaScrub typhus is caused by intracellular bacteria belonging to the genus <i>Orientia</i>. Until 2010, the endemic region was thought to be restricted to the Asia–Pacific region. <i>Orientia</i> species have recently been discovered in South America, Africa, Europe, and North America. In accordance with these circumstances, we tried to find new or novel bacterial strains in the Republic of Korea (ROK). We found that a new strain of <i>O. tsutsugamushi</i> formed a unique clade based on a 56-kDa type-specific antigen gene and showed 63.2–77.8% similarity to other strains of the same species. Additionally, we identified another sequence with 99.8% similarity to the O3 strain, which has not been recorded in the ROK and whose pathogenicity remains unknown. These findings confirm the diversity of <i>O. tsutsugamushi</i> strains in the ROK, and highlight the need for continued surveillance and further studies to characterize the pathogenicity of this novel bacterial strain.https://www.mdpi.com/2076-0817/14/1/29<i>Orientia tsutsugamushi</i>novel strainchigger mites |
| spellingShingle | Hak Seon Lee Seong Yoon Kim Hee Il Lee A Novel Strain of <i>Orientia tsutsugamushi</i> Detected from Chiggers (Acari: Trombiculidae) on Wild Rodents Pathogens <i>Orientia tsutsugamushi</i> novel strain chigger mites |
| title | A Novel Strain of <i>Orientia tsutsugamushi</i> Detected from Chiggers (Acari: Trombiculidae) on Wild Rodents |
| title_full | A Novel Strain of <i>Orientia tsutsugamushi</i> Detected from Chiggers (Acari: Trombiculidae) on Wild Rodents |
| title_fullStr | A Novel Strain of <i>Orientia tsutsugamushi</i> Detected from Chiggers (Acari: Trombiculidae) on Wild Rodents |
| title_full_unstemmed | A Novel Strain of <i>Orientia tsutsugamushi</i> Detected from Chiggers (Acari: Trombiculidae) on Wild Rodents |
| title_short | A Novel Strain of <i>Orientia tsutsugamushi</i> Detected from Chiggers (Acari: Trombiculidae) on Wild Rodents |
| title_sort | novel strain of i orientia tsutsugamushi i detected from chiggers acari trombiculidae on wild rodents |
| topic | <i>Orientia tsutsugamushi</i> novel strain chigger mites |
| url | https://www.mdpi.com/2076-0817/14/1/29 |
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