Neuromodulation possibilities in neurogenic lower urinary tract dysfunction

Introduction. Neuromodulation has proven itself in the treatment of patients suffering from idiopathic overactive bladder and non-obstructive urinary retention, who are resistant to conservative therapy. The possible use of the method in the population of patients with neurogenic lower urinary tract...

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Main Authors: G. Yu. Yarin, E. I. Kreydin, R. V. Salyukov, E. V. Kasatonova, S. V. Astrakov, A. V. Bershadsky, I. A. Vilgelmi, A. I. Shevela
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Language:Russian
Published: Ministry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional Education 2022-10-01
Series:Вестник урологии
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Online Access:https://www.urovest.ru/jour/article/view/586
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author G. Yu. Yarin
E. I. Kreydin
R. V. Salyukov
E. V. Kasatonova
S. V. Astrakov
A. V. Bershadsky
I. A. Vilgelmi
A. I. Shevela
author_facet G. Yu. Yarin
E. I. Kreydin
R. V. Salyukov
E. V. Kasatonova
S. V. Astrakov
A. V. Bershadsky
I. A. Vilgelmi
A. I. Shevela
author_sort G. Yu. Yarin
collection DOAJ
description Introduction. Neuromodulation has proven itself in the treatment of patients suffering from idiopathic overactive bladder and non-obstructive urinary retention, who are resistant to conservative therapy. The possible use of the method in the population of patients with neurogenic lower urinary tract dysfunction (NLUTD) is of undoubted clinical interest.Objective. To analyze the current possibilities and features of neuromodulation in a cohort of patients with NLUTD.Materials and methods. Original research materials published in the PubMed, eLibrary, SciVerse (ScienceDirect), Scopus, Medline, EMBASE databases, websites of professional associations without restrictions on the date of publication were used. Sixty sources were selected for citation, with preference given to systematic reviews, meta-analyses and RCTs .Results. In relation to NLUTD, transcranial and peripheral magnetic stimulation, intravesical electrical stimulation, tibial, pudendal electrical stimulation, and stimulation of the dorsal pudendal nerve, as well as sacral and epidural methods of neurostimulation are considered.Conclusion. The current literature optimistically presents the experience of using neuromodulation in the NLUTD patient population with the largest evidence base for invasive sacral and tibial stimulation. The studies are based on heterogeneous populations, limited by small sample sizes with insufficient descriptive part of the degree and severity of neurological diseases, and it should be considered when forming guidelines. However, the lack of other suitable therapies and promising initial results indicate the importance of further efforts to improve the applied methods of neuromodulation. Further studies are needed with larger sample sizes, better classification of diseases, and controlled study design
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spelling doaj-art-d5aebe4b96fe47eba53c894d9ac3cd1e2025-08-20T03:43:33ZrusMinistry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional EducationВестник урологии2308-64242022-10-0110310612110.21886/2308-6424-2022-10-3-106-121391Neuromodulation possibilities in neurogenic lower urinary tract dysfunctionG. Yu. Yarin0E. I. Kreydin1R. V. Salyukov2E. V. Kasatonova3S. V. Astrakov4A. V. Bershadsky5I. A. Vilgelmi6A. I. Shevela7«Alliance of Surgeons», LLCDepartment of Urology, Keck School of Medicine, University of Southern CaliforniaPeoples' Friendship University of Russia (RUDN University)Lopatkin Scientific Research Institute of Urology and Interventional Radiology — branch of the National Medical Research Radiological CenterNovosibirsk State Medical UniversityYekaterinburg Central City Clinical Hospital No. 6«Alliance of Surgeons», LLCInstitute of Сhemical Biology and Fundamental Medicine — the Siberian Branch of the RASIntroduction. Neuromodulation has proven itself in the treatment of patients suffering from idiopathic overactive bladder and non-obstructive urinary retention, who are resistant to conservative therapy. The possible use of the method in the population of patients with neurogenic lower urinary tract dysfunction (NLUTD) is of undoubted clinical interest.Objective. To analyze the current possibilities and features of neuromodulation in a cohort of patients with NLUTD.Materials and methods. Original research materials published in the PubMed, eLibrary, SciVerse (ScienceDirect), Scopus, Medline, EMBASE databases, websites of professional associations without restrictions on the date of publication were used. Sixty sources were selected for citation, with preference given to systematic reviews, meta-analyses and RCTs .Results. In relation to NLUTD, transcranial and peripheral magnetic stimulation, intravesical electrical stimulation, tibial, pudendal electrical stimulation, and stimulation of the dorsal pudendal nerve, as well as sacral and epidural methods of neurostimulation are considered.Conclusion. The current literature optimistically presents the experience of using neuromodulation in the NLUTD patient population with the largest evidence base for invasive sacral and tibial stimulation. The studies are based on heterogeneous populations, limited by small sample sizes with insufficient descriptive part of the degree and severity of neurological diseases, and it should be considered when forming guidelines. However, the lack of other suitable therapies and promising initial results indicate the importance of further efforts to improve the applied methods of neuromodulation. Further studies are needed with larger sample sizes, better classification of diseases, and controlled study designhttps://www.urovest.ru/jour/article/view/586neurogenic lower urinary tract dysfunctionmagnetic stimulationelectric stimulationneuromodulationneurorehabilitation
spellingShingle G. Yu. Yarin
E. I. Kreydin
R. V. Salyukov
E. V. Kasatonova
S. V. Astrakov
A. V. Bershadsky
I. A. Vilgelmi
A. I. Shevela
Neuromodulation possibilities in neurogenic lower urinary tract dysfunction
Вестник урологии
neurogenic lower urinary tract dysfunction
magnetic stimulation
electric stimulation
neuromodulation
neurorehabilitation
title Neuromodulation possibilities in neurogenic lower urinary tract dysfunction
title_full Neuromodulation possibilities in neurogenic lower urinary tract dysfunction
title_fullStr Neuromodulation possibilities in neurogenic lower urinary tract dysfunction
title_full_unstemmed Neuromodulation possibilities in neurogenic lower urinary tract dysfunction
title_short Neuromodulation possibilities in neurogenic lower urinary tract dysfunction
title_sort neuromodulation possibilities in neurogenic lower urinary tract dysfunction
topic neurogenic lower urinary tract dysfunction
magnetic stimulation
electric stimulation
neuromodulation
neurorehabilitation
url https://www.urovest.ru/jour/article/view/586
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AT rvsalyukov neuromodulationpossibilitiesinneurogeniclowerurinarytractdysfunction
AT evkasatonova neuromodulationpossibilitiesinneurogeniclowerurinarytractdysfunction
AT svastrakov neuromodulationpossibilitiesinneurogeniclowerurinarytractdysfunction
AT avbershadsky neuromodulationpossibilitiesinneurogeniclowerurinarytractdysfunction
AT iavilgelmi neuromodulationpossibilitiesinneurogeniclowerurinarytractdysfunction
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