Molecular mechanisms and consequences of TDP-43 phosphorylation in neurodegeneration
Abstract Increased phosphorylation of TDP-43 is a pathological hallmark of several neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). However, the regulation and roles of TDP-43 phosphorylation remain incompletely understood. A variety of te...
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| Main Authors: | Elise A. Kellett, Adekunle T. Bademosi, Adam K. Walker |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | Molecular Neurodegeneration |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13024-025-00839-8 |
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