C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis

Conclusion: The results of our study suggest that CRP may not directly mediate ulcerative colitis. Instead, it is more likely to be a bystander that is present alongside with elevated inflammatory factors. Further investigation is warranted to determine the precise role of CRP in humans, given the s...

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Main Authors: Zhong-Bo Ge, Xin-Yun Zhang, Chun-Miao Zhang, Tao-Tao Xu, Si-Yi Li, Meng-Xiao Wei, Xin-Yuan Ding, Cai-Juan Bai, Han Wang, Hai-Hong Zhou, Ming-Yu Wang
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2024/1386147
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Summary:Conclusion: The results of our study suggest that CRP may not directly mediate ulcerative colitis. Instead, it is more likely to be a bystander that is present alongside with elevated inflammatory factors. Further investigation is warranted to determine the precise role of CRP in humans, given the significant limitations associated with the use of mouse models.
ISSN:1687-630X