Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report

Radiofrequency ablation (RFA) plays a crucial role in the treatment of benign thyroid nodules by offering a minimally invasive alternative to surgical interventions. Nodule rupture is an uncommon complication of RFA. We present a case of nodule rupture and hyperthyroidism after RFA 41 days in a 45-y...

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Main Authors: Le Thi My, MD, Tran Thi Hoang Anh, MD, Nguyen Thi Thanh Hien, MD, Vu Mai Quynh, MD, Ngo Thi Thanh Tu, MD, Pham Vu Hiep, MD, Ngo Van Doan, PhD, Duong Manh Cuong, MD, Thieu Thi Tra My, MD
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043325005679
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author Le Thi My, MD
Tran Thi Hoang Anh, MD
Nguyen Thi Thanh Hien, MD
Vu Mai Quynh, MD
Ngo Thi Thanh Tu, MD
Pham Vu Hiep, MD
Ngo Van Doan, PhD
Duong Manh Cuong, MD
Thieu Thi Tra My, MD
author_facet Le Thi My, MD
Tran Thi Hoang Anh, MD
Nguyen Thi Thanh Hien, MD
Vu Mai Quynh, MD
Ngo Thi Thanh Tu, MD
Pham Vu Hiep, MD
Ngo Van Doan, PhD
Duong Manh Cuong, MD
Thieu Thi Tra My, MD
author_sort Le Thi My, MD
collection DOAJ
description Radiofrequency ablation (RFA) plays a crucial role in the treatment of benign thyroid nodules by offering a minimally invasive alternative to surgical interventions. Nodule rupture is an uncommon complication of RFA. We present a case of nodule rupture and hyperthyroidism after RFA 41 days in a 45-year-old male patient. The neck ultrasound revealed the disruption of the thyroid nodule capsule and a mass adjacent to the thyroid nodule. Thyroid function tests suggested of hyperthyroidism. The patient was received conservative treatment. Follow-up, the biochemical tests showed TSH and FT4 returned to normal limits 2 weeks later. Five months after radiofrequency ablation shows the thyroid nodule was decrease 92% volume compared to the volume immediately postablation and the soft tissue lesion in the right neck region was completely regressed.
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publisher Elsevier
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series Radiology Case Reports
spelling doaj-art-d5a7954881f044f3bcd62169c29656dd2025-08-20T02:36:46ZengElsevierRadiology Case Reports1930-04332025-09-012094807481110.1016/j.radcr.2025.06.020Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case reportLe Thi My, MD0Tran Thi Hoang Anh, MD1Nguyen Thi Thanh Hien, MD2Vu Mai Quynh, MD3Ngo Thi Thanh Tu, MD4Pham Vu Hiep, MD5Ngo Van Doan, PhD6Duong Manh Cuong, MD7Thieu Thi Tra My, MD8Radiology Department, Vinmec Times City International hospital, Vinmec Healthcare System, Hanoi, VietnamRadiology Department, Vinmec Times City International hospital, Vinmec Healthcare System, Hanoi, VietnamRadiology department, Radiology Residency Program VinUniversity, VinUniversity, Hanoi, VietnamRadiology department, Radiology Residency Program VinUniversity, VinUniversity, Hanoi, VietnamRadiology Department, Vinmec Times City International hospital, Vinmec Healthcare System, Hanoi, VietnamRadiology Department, Vinmec Times City International hospital, Vinmec Healthcare System, Hanoi, VietnamRadiology Department, Vinmec Times City International hospital, Vinmec Healthcare System, Hanoi, VietnamGeneral Internal Medicine Department, Vinmec Times City International hospital, Vinmec Healthcare System, Hanoi, VietnamRadiology Department, Vinmec Times City International hospital, Vinmec Healthcare System, Hanoi, Vietnam; Corresponding author.Radiofrequency ablation (RFA) plays a crucial role in the treatment of benign thyroid nodules by offering a minimally invasive alternative to surgical interventions. Nodule rupture is an uncommon complication of RFA. We present a case of nodule rupture and hyperthyroidism after RFA 41 days in a 45-year-old male patient. The neck ultrasound revealed the disruption of the thyroid nodule capsule and a mass adjacent to the thyroid nodule. Thyroid function tests suggested of hyperthyroidism. The patient was received conservative treatment. Follow-up, the biochemical tests showed TSH and FT4 returned to normal limits 2 weeks later. Five months after radiofrequency ablation shows the thyroid nodule was decrease 92% volume compared to the volume immediately postablation and the soft tissue lesion in the right neck region was completely regressed.http://www.sciencedirect.com/science/article/pii/S1930043325005679Thyroid nodule ruptureHyperthyroidismRadiofrequency ablation
spellingShingle Le Thi My, MD
Tran Thi Hoang Anh, MD
Nguyen Thi Thanh Hien, MD
Vu Mai Quynh, MD
Ngo Thi Thanh Tu, MD
Pham Vu Hiep, MD
Ngo Van Doan, PhD
Duong Manh Cuong, MD
Thieu Thi Tra My, MD
Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report
Radiology Case Reports
Thyroid nodule rupture
Hyperthyroidism
Radiofrequency ablation
title Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report
title_full Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report
title_fullStr Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report
title_full_unstemmed Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report
title_short Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report
title_sort thyroid nodule rupture and hyperthyroidism following radiofrequency ablation a case report
topic Thyroid nodule rupture
Hyperthyroidism
Radiofrequency ablation
url http://www.sciencedirect.com/science/article/pii/S1930043325005679
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