Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia.
With the purpose to estimate influence of comorbidity at the risk of complications and death due to community-acquired pneumonia (CAP) the retrospective analysis of 1587 case histories of inpatients with CAP (mean age – 48.5±18.4, males – 815 (51.4%), women – 772 (48,6%)) was performed. Comorbidity...
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| Format: | Article |
| Language: | English |
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Dnipro State Medical University
2018-04-01
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| Series: | Medičnì Perspektivi |
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| Online Access: | http://journals.uran.ua/index.php/2307-0404/article/view/127248 |
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| author | Y. M. Mostovoy A. V. Demchuk T. V. Konstantynovych K. D. Chichirelo-Konstantynovych |
| author_facet | Y. M. Mostovoy A. V. Demchuk T. V. Konstantynovych K. D. Chichirelo-Konstantynovych |
| author_sort | Y. M. Mostovoy |
| collection | DOAJ |
| description | With the purpose to estimate influence of comorbidity at the risk of complications and death due to community-acquired pneumonia (CAP) the retrospective analysis of 1587 case histories of inpatients with CAP (mean age – 48.5±18.4, males – 815 (51.4%), women – 772 (48,6%)) was performed. Comorbidity was observed in 1114 (70.2%). More frequently complications of CAP were developed in patients with chronic diseases than without them (p=0.013). Increased risk of pleural effusion was associated with chronic diseases of digestive system (OR=1.85 (95%CI 1.30-2.26)) and diabetes mellitus (OR=2.35 (95%CI 1.40-3.96)). Risk of sepsis development is higher in patients with nervous system diseases (OR=3.62 (95%CI 1.37-9.56) and drug or alcohol addiction (OR=19.08 (95%CI 7.30-49.82). Risk of pulmonary edema rose in patients with drug or alcohol addiction (OR=24.16; 95%CI 8.07-72.34), malignancy (OR=8.97; 95%CI 1.94-41.49), diabetes mellitus (OR=4.04; 95%CI 1.48-11.01), diseases of nervous (OR=4.04; 95%CI 1.17-13.94), urinary (OR=3.39; 95%CI 1.33-8.64) and cardiovascular (OR=2.29, 95%CI 0.98-5.34) systems. Higher risk of death in patients with CAP was associated with the presence of cardiovascular diseases (OR=2.17; 95%CI 1.11-4.25), diabetes mellitus (OR=2.95; 95%CI 1.20-7.21), drug or alcohol addiction (OR=38.40; 95%CI 15.05-97.98). |
| format | Article |
| id | doaj-art-d5a57428ec3342e1b3f4ddbb91ccb624 |
| institution | OA Journals |
| issn | 2307-0404 |
| language | English |
| publishDate | 2018-04-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj-art-d5a57428ec3342e1b3f4ddbb91ccb6242025-08-20T02:38:52ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042018-04-01231(part1)11211710.26641/2307-0404.2018.1(part1).127248127248Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia.Y. M. MostovoyA. V. DemchukT. V. KonstantynovychK. D. Chichirelo-KonstantynovychWith the purpose to estimate influence of comorbidity at the risk of complications and death due to community-acquired pneumonia (CAP) the retrospective analysis of 1587 case histories of inpatients with CAP (mean age – 48.5±18.4, males – 815 (51.4%), women – 772 (48,6%)) was performed. Comorbidity was observed in 1114 (70.2%). More frequently complications of CAP were developed in patients with chronic diseases than without them (p=0.013). Increased risk of pleural effusion was associated with chronic diseases of digestive system (OR=1.85 (95%CI 1.30-2.26)) and diabetes mellitus (OR=2.35 (95%CI 1.40-3.96)). Risk of sepsis development is higher in patients with nervous system diseases (OR=3.62 (95%CI 1.37-9.56) and drug or alcohol addiction (OR=19.08 (95%CI 7.30-49.82). Risk of pulmonary edema rose in patients with drug or alcohol addiction (OR=24.16; 95%CI 8.07-72.34), malignancy (OR=8.97; 95%CI 1.94-41.49), diabetes mellitus (OR=4.04; 95%CI 1.48-11.01), diseases of nervous (OR=4.04; 95%CI 1.17-13.94), urinary (OR=3.39; 95%CI 1.33-8.64) and cardiovascular (OR=2.29, 95%CI 0.98-5.34) systems. Higher risk of death in patients with CAP was associated with the presence of cardiovascular diseases (OR=2.17; 95%CI 1.11-4.25), diabetes mellitus (OR=2.95; 95%CI 1.20-7.21), drug or alcohol addiction (OR=38.40; 95%CI 15.05-97.98).http://journals.uran.ua/index.php/2307-0404/article/view/127248community-acquired pneumoniachronic diseases of internal organs |
| spellingShingle | Y. M. Mostovoy A. V. Demchuk T. V. Konstantynovych K. D. Chichirelo-Konstantynovych Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia. Medičnì Perspektivi community-acquired pneumonia chronic diseases of internal organs |
| title | Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia. |
| title_full | Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia. |
| title_fullStr | Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia. |
| title_full_unstemmed | Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia. |
| title_short | Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia. |
| title_sort | chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community acquired pneumonia |
| topic | community-acquired pneumonia chronic diseases of internal organs |
| url | http://journals.uran.ua/index.php/2307-0404/article/view/127248 |
| work_keys_str_mv | AT ymmostovoy chroniccomorbidityofinternalorgansasariskfactorofcomplicationsandfataloutcomeofcommunityacquiredpneumonia AT avdemchuk chroniccomorbidityofinternalorgansasariskfactorofcomplicationsandfataloutcomeofcommunityacquiredpneumonia AT tvkonstantynovych chroniccomorbidityofinternalorgansasariskfactorofcomplicationsandfataloutcomeofcommunityacquiredpneumonia AT kdchichirelokonstantynovych chroniccomorbidityofinternalorgansasariskfactorofcomplicationsandfataloutcomeofcommunityacquiredpneumonia |