REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)
Rapid eye movement sleep behavior disorder (RBD) is a parasomnia, with abnormal dream-enacting behavior during the rapid eye movement (REM) sleep. RBD is either idiopathic or secondary to other neurologic disorders and medications. Dementia with Lewy bodies (DLB) is the third most common cause of de...
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Wiley
2018-01-01
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Series: | Behavioural Neurology |
Online Access: | http://dx.doi.org/10.1155/2018/9421098 |
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author | Po-Chi Chan Hsun-Hua Lee Chien-Tai Hong Chaur-Jong Hu Dean Wu |
author_facet | Po-Chi Chan Hsun-Hua Lee Chien-Tai Hong Chaur-Jong Hu Dean Wu |
author_sort | Po-Chi Chan |
collection | DOAJ |
description | Rapid eye movement sleep behavior disorder (RBD) is a parasomnia, with abnormal dream-enacting behavior during the rapid eye movement (REM) sleep. RBD is either idiopathic or secondary to other neurologic disorders and medications. Dementia with Lewy bodies (DLB) is the third most common cause of dementia, and the typical clinical presentation is rapidly progressive cognitive impairment. RBD is one of the core features of DLB and may occur either in advance or simultaneously with the onset of DLB. The association between RBD with DLB is widely studied. Evidences suggest that both DLB and RBD are possibly caused by the shared underlying synucleinopathy. This review article discusses history, clinical manifestations, possible pathophysiologies, and treatment of DLB and RBD and provides the latest updates. |
format | Article |
id | doaj-art-d5a265ba6316416c913df617fdbbf32a |
institution | Kabale University |
issn | 0953-4180 1875-8584 |
language | English |
publishDate | 2018-01-01 |
publisher | Wiley |
record_format | Article |
series | Behavioural Neurology |
spelling | doaj-art-d5a265ba6316416c913df617fdbbf32a2025-02-03T05:49:21ZengWileyBehavioural Neurology0953-41801875-85842018-01-01201810.1155/2018/94210989421098REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)Po-Chi Chan0Hsun-Hua Lee1Chien-Tai Hong2Chaur-Jong Hu3Dean Wu4Department of Neurology, Show Chwan Memorial Hospital, Changhua, TaiwanDepartment of Neurology, Taipei Medical University Shuang Ho Hospital, New Taipei City, TaiwanDepartment of Neurology, Taipei Medical University Shuang Ho Hospital, New Taipei City, TaiwanDepartment of Neurology, Taipei Medical University Shuang Ho Hospital, New Taipei City, TaiwanDepartment of Neurology, Taipei Medical University Shuang Ho Hospital, New Taipei City, TaiwanRapid eye movement sleep behavior disorder (RBD) is a parasomnia, with abnormal dream-enacting behavior during the rapid eye movement (REM) sleep. RBD is either idiopathic or secondary to other neurologic disorders and medications. Dementia with Lewy bodies (DLB) is the third most common cause of dementia, and the typical clinical presentation is rapidly progressive cognitive impairment. RBD is one of the core features of DLB and may occur either in advance or simultaneously with the onset of DLB. The association between RBD with DLB is widely studied. Evidences suggest that both DLB and RBD are possibly caused by the shared underlying synucleinopathy. This review article discusses history, clinical manifestations, possible pathophysiologies, and treatment of DLB and RBD and provides the latest updates.http://dx.doi.org/10.1155/2018/9421098 |
spellingShingle | Po-Chi Chan Hsun-Hua Lee Chien-Tai Hong Chaur-Jong Hu Dean Wu REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB) Behavioural Neurology |
title | REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB) |
title_full | REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB) |
title_fullStr | REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB) |
title_full_unstemmed | REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB) |
title_short | REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB) |
title_sort | rem sleep behavior disorder rbd in dementia with lewy bodies dlb |
url | http://dx.doi.org/10.1155/2018/9421098 |
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