REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)

Rapid eye movement sleep behavior disorder (RBD) is a parasomnia, with abnormal dream-enacting behavior during the rapid eye movement (REM) sleep. RBD is either idiopathic or secondary to other neurologic disorders and medications. Dementia with Lewy bodies (DLB) is the third most common cause of de...

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Main Authors: Po-Chi Chan, Hsun-Hua Lee, Chien-Tai Hong, Chaur-Jong Hu, Dean Wu
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2018/9421098
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author Po-Chi Chan
Hsun-Hua Lee
Chien-Tai Hong
Chaur-Jong Hu
Dean Wu
author_facet Po-Chi Chan
Hsun-Hua Lee
Chien-Tai Hong
Chaur-Jong Hu
Dean Wu
author_sort Po-Chi Chan
collection DOAJ
description Rapid eye movement sleep behavior disorder (RBD) is a parasomnia, with abnormal dream-enacting behavior during the rapid eye movement (REM) sleep. RBD is either idiopathic or secondary to other neurologic disorders and medications. Dementia with Lewy bodies (DLB) is the third most common cause of dementia, and the typical clinical presentation is rapidly progressive cognitive impairment. RBD is one of the core features of DLB and may occur either in advance or simultaneously with the onset of DLB. The association between RBD with DLB is widely studied. Evidences suggest that both DLB and RBD are possibly caused by the shared underlying synucleinopathy. This review article discusses history, clinical manifestations, possible pathophysiologies, and treatment of DLB and RBD and provides the latest updates.
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institution Kabale University
issn 0953-4180
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publishDate 2018-01-01
publisher Wiley
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series Behavioural Neurology
spelling doaj-art-d5a265ba6316416c913df617fdbbf32a2025-02-03T05:49:21ZengWileyBehavioural Neurology0953-41801875-85842018-01-01201810.1155/2018/94210989421098REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)Po-Chi Chan0Hsun-Hua Lee1Chien-Tai Hong2Chaur-Jong Hu3Dean Wu4Department of Neurology, Show Chwan Memorial Hospital, Changhua, TaiwanDepartment of Neurology, Taipei Medical University Shuang Ho Hospital, New Taipei City, TaiwanDepartment of Neurology, Taipei Medical University Shuang Ho Hospital, New Taipei City, TaiwanDepartment of Neurology, Taipei Medical University Shuang Ho Hospital, New Taipei City, TaiwanDepartment of Neurology, Taipei Medical University Shuang Ho Hospital, New Taipei City, TaiwanRapid eye movement sleep behavior disorder (RBD) is a parasomnia, with abnormal dream-enacting behavior during the rapid eye movement (REM) sleep. RBD is either idiopathic or secondary to other neurologic disorders and medications. Dementia with Lewy bodies (DLB) is the third most common cause of dementia, and the typical clinical presentation is rapidly progressive cognitive impairment. RBD is one of the core features of DLB and may occur either in advance or simultaneously with the onset of DLB. The association between RBD with DLB is widely studied. Evidences suggest that both DLB and RBD are possibly caused by the shared underlying synucleinopathy. This review article discusses history, clinical manifestations, possible pathophysiologies, and treatment of DLB and RBD and provides the latest updates.http://dx.doi.org/10.1155/2018/9421098
spellingShingle Po-Chi Chan
Hsun-Hua Lee
Chien-Tai Hong
Chaur-Jong Hu
Dean Wu
REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)
Behavioural Neurology
title REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)
title_full REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)
title_fullStr REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)
title_full_unstemmed REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)
title_short REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)
title_sort rem sleep behavior disorder rbd in dementia with lewy bodies dlb
url http://dx.doi.org/10.1155/2018/9421098
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