Digital twin for personalized medicine development

Digital Twin (DT) technology is revolutionizing healthcare by enabling real-time monitoring, predictive analytics, and highly personalized medical care. As a key innovation of Industry 4.0, DTs integrate advanced tools like artificial intelligence (AI), the Internet of Things (IoT), and machine lear...

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Main Authors: Saniya Y. Saratkar, Meher Langote, Praveen Kumar, Pradnyawant Gote, Induni Nayodhara Weerarathna, Gaurav V. Mishra
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Digital Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fdgth.2025.1583466/full
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author Saniya Y. Saratkar
Meher Langote
Praveen Kumar
Pradnyawant Gote
Induni Nayodhara Weerarathna
Gaurav V. Mishra
author_facet Saniya Y. Saratkar
Meher Langote
Praveen Kumar
Pradnyawant Gote
Induni Nayodhara Weerarathna
Gaurav V. Mishra
author_sort Saniya Y. Saratkar
collection DOAJ
description Digital Twin (DT) technology is revolutionizing healthcare by enabling real-time monitoring, predictive analytics, and highly personalized medical care. As a key innovation of Industry 4.0, DTs integrate advanced tools like artificial intelligence (AI), the Internet of Things (IoT), and machine learning (ML) to create dynamic, data-driven replicas of patients. These digital replicas allow simulations of disease progression, optimize diagnostics, and personalize treatment plans based on individual genetic and lifestyle profiles. This review explores the evolution, architecture, and enabling technologies of DTs, focusing on their transformative applications in personalized medicine (PM). While the integration of DTs offers immense potential to improve outcomes and efficiency in healthcare, challenges such as data privacy, system interoperability, and ethical concerns must be addressed. The paper concludes by highlighting future directions, where AI, cloud computing, and blockchain are expected to play a pivotal role in overcoming these limitations and advancing precision medicine.
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publishDate 2025-08-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Digital Health
spelling doaj-art-d59b2be863f3428ca226f14e7f7222e72025-08-20T03:41:00ZengFrontiers Media S.A.Frontiers in Digital Health2673-253X2025-08-01710.3389/fdgth.2025.15834661583466Digital twin for personalized medicine developmentSaniya Y. Saratkar0Meher Langote1Praveen Kumar2Pradnyawant Gote3Induni Nayodhara Weerarathna4Gaurav V. Mishra5Department of Artificial Intelligence and Data Science, Faculty of Engineering and Technology, Datta Meghe Institute of Higher Education and Research, Wardha, IndiaDepartment of Artificial Intelligence and Data Science, Faculty of Engineering and Technology, Datta Meghe Institute of Higher Education and Research, Wardha, IndiaDepartment of Computer Science Medical Engineering, Faculty of Engineering and Technology, Datta Meghe Institute of Higher Education and Research, Wardha, IndiaDepartment of Computer Science and Departments, Faculty of Engineering and Technology, Datta Meghe Institute of Higher Education and Research, Wardha, IndiaDepartment of Biomedical Sciences, Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, IndiaDepartment of Radiodiagnosis, Datta Meghe Institute of Higher Education and Research, Wardha, IndiaDigital Twin (DT) technology is revolutionizing healthcare by enabling real-time monitoring, predictive analytics, and highly personalized medical care. As a key innovation of Industry 4.0, DTs integrate advanced tools like artificial intelligence (AI), the Internet of Things (IoT), and machine learning (ML) to create dynamic, data-driven replicas of patients. These digital replicas allow simulations of disease progression, optimize diagnostics, and personalize treatment plans based on individual genetic and lifestyle profiles. This review explores the evolution, architecture, and enabling technologies of DTs, focusing on their transformative applications in personalized medicine (PM). While the integration of DTs offers immense potential to improve outcomes and efficiency in healthcare, challenges such as data privacy, system interoperability, and ethical concerns must be addressed. The paper concludes by highlighting future directions, where AI, cloud computing, and blockchain are expected to play a pivotal role in overcoming these limitations and advancing precision medicine.https://www.frontiersin.org/articles/10.3389/fdgth.2025.1583466/fulldigital twinpersonalized medicineartificial intelligencehealthcareinternet of things (IoT)
spellingShingle Saniya Y. Saratkar
Meher Langote
Praveen Kumar
Pradnyawant Gote
Induni Nayodhara Weerarathna
Gaurav V. Mishra
Digital twin for personalized medicine development
Frontiers in Digital Health
digital twin
personalized medicine
artificial intelligence
healthcare
internet of things (IoT)
title Digital twin for personalized medicine development
title_full Digital twin for personalized medicine development
title_fullStr Digital twin for personalized medicine development
title_full_unstemmed Digital twin for personalized medicine development
title_short Digital twin for personalized medicine development
title_sort digital twin for personalized medicine development
topic digital twin
personalized medicine
artificial intelligence
healthcare
internet of things (IoT)
url https://www.frontiersin.org/articles/10.3389/fdgth.2025.1583466/full
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