Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024
Dengue, caused by the dengue virus (DENV), is the fastest-growing mosquito-borne disease worldwide. We utilised monthly data on dengue cases and deaths reported through the World Health Organisation's (WHO) global surveillance system for the period of 1st January to 31st December 2024. We then...
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Elsevier
2025-09-01
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| Series: | International Journal of Infectious Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S120197122500164X |
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| author | Najmul Haider Mohammad Nayeem Hasan Joshua Onyango Masum Billah Sakirul Khan Danai Papakonstantinou Priyamvada Paudyal Md Asaduzzaman |
| author_facet | Najmul Haider Mohammad Nayeem Hasan Joshua Onyango Masum Billah Sakirul Khan Danai Papakonstantinou Priyamvada Paudyal Md Asaduzzaman |
| author_sort | Najmul Haider |
| collection | DOAJ |
| description | Dengue, caused by the dengue virus (DENV), is the fastest-growing mosquito-borne disease worldwide. We utilised monthly data on dengue cases and deaths reported through the World Health Organisation's (WHO) global surveillance system for the period of 1st January to 31st December 2024. We then performed a generalised linear regression model to understand country-level determinants of dengue-related mortality. In 2024, 14.1 million dengue cases were reported globally, surpassing the historic milestone of 7 million observed in 2023. This figure represents a twofold increase compared to 2023 and a 12-fold rise compared to 2014 (n=1,206,644). In 2024, 9,508 dengue-related deaths were recorded, resulting in a global case-fatality rate of 0.07%. In the regression analysis, countries in the Southern hemisphere (incidence rate ratio [IRR]: 5.95, 95% CI: 4.19-8.46), aged population (IRR 1.04, CI: 1.01-1.07), and mean annual temperature (IRR 1.21, CI: 1.16-1.26) were significantly associated with higher dengue-related mortality per million population. The ongoing dengue outbreak underscores the urgent need for global investment in DENV research, vaccine development, vector control, and therapeutic strategies. We urge the inclusion of DENV in the WHO’s Research and Development Priority Disease list to address this growing global health threat. |
| format | Article |
| id | doaj-art-d59a8dbca7a44e2b91dd3253fa173486 |
| institution | Kabale University |
| issn | 1201-9712 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj-art-d59a8dbca7a44e2b91dd3253fa1734862025-08-20T03:42:52ZengElsevierInternational Journal of Infectious Diseases1201-97122025-09-0115810794010.1016/j.ijid.2025.107940Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024Najmul Haider0Mohammad Nayeem Hasan1Joshua Onyango2Masum Billah3Sakirul Khan4Danai Papakonstantinou5Priyamvada Paudyal6Md Asaduzzaman7School of Life Sciences, Faculty of Natural Sciences, Keele University, Keele, Staffordshire, ST5 5BG, United Kingdom; Corresponding: Najmul Haider, School of Life Sciences, Faculty of Natural Sciences, Keele University, Keele, Staffordshire, United Kingdom, ST5 5BG.Department of Statistics, Shahjalal University of Science and Technology, Sylhet, BangladeshThe Harper and Keele Veterinary School, Keele University, Keele, Staffordshire, United KingdomDepartment of Engineering, University of Staffordshire, Stoke-on-Trent, ST4 2DE, United KingdomResearch Center for Global and Local Infectious Diseases, Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Oita, JapanSchool of Medicine, Keele University, Keele, Staffordshire, UKInstitute for Global Health and Wellbeing, School of Medicine, Keele University, Keele, Staffordshire, UKDepartment of Engineering, University of Staffordshire, Stoke-on-Trent, ST4 2DE, United KingdomDengue, caused by the dengue virus (DENV), is the fastest-growing mosquito-borne disease worldwide. We utilised monthly data on dengue cases and deaths reported through the World Health Organisation's (WHO) global surveillance system for the period of 1st January to 31st December 2024. We then performed a generalised linear regression model to understand country-level determinants of dengue-related mortality. In 2024, 14.1 million dengue cases were reported globally, surpassing the historic milestone of 7 million observed in 2023. This figure represents a twofold increase compared to 2023 and a 12-fold rise compared to 2014 (n=1,206,644). In 2024, 9,508 dengue-related deaths were recorded, resulting in a global case-fatality rate of 0.07%. In the regression analysis, countries in the Southern hemisphere (incidence rate ratio [IRR]: 5.95, 95% CI: 4.19-8.46), aged population (IRR 1.04, CI: 1.01-1.07), and mean annual temperature (IRR 1.21, CI: 1.16-1.26) were significantly associated with higher dengue-related mortality per million population. The ongoing dengue outbreak underscores the urgent need for global investment in DENV research, vaccine development, vector control, and therapeutic strategies. We urge the inclusion of DENV in the WHO’s Research and Development Priority Disease list to address this growing global health threat.http://www.sciencedirect.com/science/article/pii/S120197122500164XDengueOutbreakEpidemicGlobal BurdenWHOR&D priority list |
| spellingShingle | Najmul Haider Mohammad Nayeem Hasan Joshua Onyango Masum Billah Sakirul Khan Danai Papakonstantinou Priyamvada Paudyal Md Asaduzzaman Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024 International Journal of Infectious Diseases Dengue Outbreak Epidemic Global Burden WHO R&D priority list |
| title | Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024 |
| title_full | Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024 |
| title_fullStr | Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024 |
| title_full_unstemmed | Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024 |
| title_short | Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024 |
| title_sort | global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024 |
| topic | Dengue Outbreak Epidemic Global Burden WHO R&D priority list |
| url | http://www.sciencedirect.com/science/article/pii/S120197122500164X |
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