Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba L. (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic Rats
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| Format: | Article |
| Language: | English |
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American Chemical Society
2025-07-01
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| Series: | ACS Omega |
| Online Access: | https://doi.org/10.1021/acsomega.5c03364 |
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| author | Caina Li Yuting Ma Shengyu Wen Liran Lei Yi Huan Jiayu Zhai Kejia Xu Hui Cao Lei Lei Cunyu Feng Yuling Liu Zhufang Shen Quan Liu Shuainan Liu |
| author_facet | Caina Li Yuting Ma Shengyu Wen Liran Lei Yi Huan Jiayu Zhai Kejia Xu Hui Cao Lei Lei Cunyu Feng Yuling Liu Zhufang Shen Quan Liu Shuainan Liu |
| author_sort | Caina Li |
| collection | DOAJ |
| format | Article |
| id | doaj-art-d58e2714edd64d49bb955fe0483562c5 |
| institution | DOAJ |
| issn | 2470-1343 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | ACS Omega |
| spelling | doaj-art-d58e2714edd64d49bb955fe0483562c52025-08-20T03:03:59ZengAmerican Chemical SocietyACS Omega2470-13432025-07-011031345973460710.1021/acsomega.5c03364Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba L. (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic RatsCaina Li0Yuting Ma1Shengyu Wen2Liran Lei3Yi Huan4Jiayu Zhai5Kejia Xu6Hui Cao7Lei Lei8Cunyu Feng9Yuling Liu10Zhufang Shen11Quan Liu12Shuainan Liu13State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Chinahttps://doi.org/10.1021/acsomega.5c03364 |
| spellingShingle | Caina Li Yuting Ma Shengyu Wen Liran Lei Yi Huan Jiayu Zhai Kejia Xu Hui Cao Lei Lei Cunyu Feng Yuling Liu Zhufang Shen Quan Liu Shuainan Liu Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba L. (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic Rats ACS Omega |
| title | Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba L. (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic Rats |
| title_full | Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba L. (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic Rats |
| title_fullStr | Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba L. (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic Rats |
| title_full_unstemmed | Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba L. (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic Rats |
| title_short | Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba L. (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic Rats |
| title_sort | integration of metabolomics transcriptomics and 16s rrna sequencing reveals the mechanism of morus alba l sangzhi alkaloids sz a in improving cholesterol metabolism in diabetic rats |
| url | https://doi.org/10.1021/acsomega.5c03364 |
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