GALECTIN-3 AS A MARKER OF MYOCARDIAL FUNCTION IN MEN AGED 40-60 YEARS WITHOUT CARDIOVASCULAR PATHOLOGY, CARRIERS OF POLYMORPHIC GENES AT1R
The concentrations of galectin-3 and BNP, central and systemic hemodynamics, structural and functional heart parameters in male carriers of polymorphic AT1R genes without cardiovascular pathology (n = 79) living in Podillya region were studied. Genotyping of the AT1R gene was carried out using a pol...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Poltava State Medical University
2018-03-01
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| Series: | Проблеми екології та медицини |
| Subjects: | |
| Online Access: | https://ecomed-journal.org/index.php/journal/article/view/117 |
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| Summary: | The concentrations of galectin-3 and BNP, central and systemic hemodynamics, structural and functional heart parameters in male carriers of polymorphic AT1R genes without cardiovascular pathology (n = 79) living in Podillya region were studied. Genotyping of the AT1R gene was carried out using a polymerase chain reaction. The level of galectin-3 and BNP was determined by the method of enzyme immunoassay. It was found that the A1166A genotype dominated in practically healthy men of Podilly region. Nevertheless, the level of galectin-3 and BNP in the studied population did not significantly depend on the carriage of a specific variant of the AT1R gene. |
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| ISSN: | 2073-4662 2519-2302 |