Clinical findings and electrocardiography predicted mortality among COVID-19 patients with pre-existing hypertension: A cross-sectional study of East Java Province, Indonesia

Objective: To evaluate the factors associated with mortality among coronavirus disease-2019 patients with preexisting hypertension. Method: The retrospective, cross-sectional study was conducted from June 15 to July 7, 2021, after approval from Dr Soetomo General Province Hospital, Indonesia, and c...

Full description

Saved in:
Bibliographic Details
Main Authors: Makhyan Jibril Al Farabi, Pandit Bagus Tri Saputra, Amanda Marantika, Diar Pasahan, Runn Rami, Yudi Her Oktaviono
Format: Article
Language:English
Published: Pakistan Medical Association 2024-07-01
Series:Journal of the Pakistan Medical Association
Online Access:https://jpma.org.pk/index.php/public_html/article/view/21450
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850094423036133376
author Makhyan Jibril Al Farabi
Pandit Bagus Tri Saputra
Amanda Marantika
Diar Pasahan
Runn Rami
Yudi Her Oktaviono
author_facet Makhyan Jibril Al Farabi
Pandit Bagus Tri Saputra
Amanda Marantika
Diar Pasahan
Runn Rami
Yudi Her Oktaviono
author_sort Makhyan Jibril Al Farabi
collection DOAJ
description Objective: To evaluate the factors associated with mortality among coronavirus disease-2019 patients with preexisting hypertension. Method: The retrospective, cross-sectional study was conducted from June 15 to July 7, 2021, after approval from Dr Soetomo General Province Hospital, Indonesia, and comprised data from the coronavirus disease-2019 registry in the East Java province of Indonesia from March 2020 to June 2021. Data was collected for adult patients infected by coronavirus disease-2019 with pre-existing hypertension Data was analysed using SPSS 23. Results: Of the 2,732 patients in the registry, 425(15.6%) with median age 56.5 years (interquartile range: 50-64 years) had pre-existing hypertension. Of them, 251(59.06%) were males, and 110(25.9%) had died while in hospital. Mortality was associated with older age; higher white blood cell counts at admission and lower platelet count (p<0.05). In addition, electrocardiogram parameters associated with mortality were faster heart rate and ST abnormality (p<0.05). Conclusion: Older age, high white blood cell level, lower platelet count, faster heart rate, and ST abnormality at admission were found to be the predictors of mortality among hospitalised coronavirus disease-2019 patients with pre-existing hypertension. Key Words: COVID-19, Hypertension, Electrocardiography, Leukocytes.
format Article
id doaj-art-d58614ab052b475fa581eabcc92deb26
institution DOAJ
issn 0030-9982
language English
publishDate 2024-07-01
publisher Pakistan Medical Association
record_format Article
series Journal of the Pakistan Medical Association
spelling doaj-art-d58614ab052b475fa581eabcc92deb262025-08-20T02:41:40ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822024-07-01746 (Supple)10.47391/JPMA.S6-ACSA-03Clinical findings and electrocardiography predicted mortality among COVID-19 patients with pre-existing hypertension: A cross-sectional study of East Java Province, IndonesiaMakhyan Jibril Al Farabi0Pandit Bagus Tri Saputra1Amanda Marantika2Diar Pasahan3Runn Rami4Yudi Her Oktaviono56Department of Cardiology and Vascular Medicine, Universitas Airlangga - Dr Soetomo General Academic Hospital, Surabaya6Department of Cardiology and Vascular Medicine, Universitas Airlangga - Dr Soetomo General Academic Hospital, SurabayaFaculty of Medicine, Universitas Airlangga, Surabaya, Indonesia6Department of Cardiology and Vascular Medicine, Universitas Airlangga - Dr Soetomo General Academic Hospital, Surabaya6Department of Cardiology and Vascular Medicine, Universitas Airlangga - Dr Soetomo General Academic Hospital, Surabaya6Department of Cardiology and Vascular Medicine, Universitas Airlangga - Dr Soetomo General Academic Hospital, Surabaya Objective: To evaluate the factors associated with mortality among coronavirus disease-2019 patients with preexisting hypertension. Method: The retrospective, cross-sectional study was conducted from June 15 to July 7, 2021, after approval from Dr Soetomo General Province Hospital, Indonesia, and comprised data from the coronavirus disease-2019 registry in the East Java province of Indonesia from March 2020 to June 2021. Data was collected for adult patients infected by coronavirus disease-2019 with pre-existing hypertension Data was analysed using SPSS 23. Results: Of the 2,732 patients in the registry, 425(15.6%) with median age 56.5 years (interquartile range: 50-64 years) had pre-existing hypertension. Of them, 251(59.06%) were males, and 110(25.9%) had died while in hospital. Mortality was associated with older age; higher white blood cell counts at admission and lower platelet count (p<0.05). In addition, electrocardiogram parameters associated with mortality were faster heart rate and ST abnormality (p<0.05). Conclusion: Older age, high white blood cell level, lower platelet count, faster heart rate, and ST abnormality at admission were found to be the predictors of mortality among hospitalised coronavirus disease-2019 patients with pre-existing hypertension. Key Words: COVID-19, Hypertension, Electrocardiography, Leukocytes. https://jpma.org.pk/index.php/public_html/article/view/21450
spellingShingle Makhyan Jibril Al Farabi
Pandit Bagus Tri Saputra
Amanda Marantika
Diar Pasahan
Runn Rami
Yudi Her Oktaviono
Clinical findings and electrocardiography predicted mortality among COVID-19 patients with pre-existing hypertension: A cross-sectional study of East Java Province, Indonesia
Journal of the Pakistan Medical Association
title Clinical findings and electrocardiography predicted mortality among COVID-19 patients with pre-existing hypertension: A cross-sectional study of East Java Province, Indonesia
title_full Clinical findings and electrocardiography predicted mortality among COVID-19 patients with pre-existing hypertension: A cross-sectional study of East Java Province, Indonesia
title_fullStr Clinical findings and electrocardiography predicted mortality among COVID-19 patients with pre-existing hypertension: A cross-sectional study of East Java Province, Indonesia
title_full_unstemmed Clinical findings and electrocardiography predicted mortality among COVID-19 patients with pre-existing hypertension: A cross-sectional study of East Java Province, Indonesia
title_short Clinical findings and electrocardiography predicted mortality among COVID-19 patients with pre-existing hypertension: A cross-sectional study of East Java Province, Indonesia
title_sort clinical findings and electrocardiography predicted mortality among covid 19 patients with pre existing hypertension a cross sectional study of east java province indonesia
url https://jpma.org.pk/index.php/public_html/article/view/21450
work_keys_str_mv AT makhyanjibrilalfarabi clinicalfindingsandelectrocardiographypredictedmortalityamongcovid19patientswithpreexistinghypertensionacrosssectionalstudyofeastjavaprovinceindonesia
AT panditbagustrisaputra clinicalfindingsandelectrocardiographypredictedmortalityamongcovid19patientswithpreexistinghypertensionacrosssectionalstudyofeastjavaprovinceindonesia
AT amandamarantika clinicalfindingsandelectrocardiographypredictedmortalityamongcovid19patientswithpreexistinghypertensionacrosssectionalstudyofeastjavaprovinceindonesia
AT diarpasahan clinicalfindingsandelectrocardiographypredictedmortalityamongcovid19patientswithpreexistinghypertensionacrosssectionalstudyofeastjavaprovinceindonesia
AT runnrami clinicalfindingsandelectrocardiographypredictedmortalityamongcovid19patientswithpreexistinghypertensionacrosssectionalstudyofeastjavaprovinceindonesia
AT yudiheroktaviono clinicalfindingsandelectrocardiographypredictedmortalityamongcovid19patientswithpreexistinghypertensionacrosssectionalstudyofeastjavaprovinceindonesia