Severe Drug-Induced Agranulocytosis Successfully Treated with Recombinant Human Granulocyte Colony-Stimulating Factor
When elderly patients are prescribed many different medications, the risk for developing serious adverse events should be kept in mind. One of these adverse events is agranulocytosis, which, although rare, can be life-threatening if left untreated. The majority of agranulocytosis cases are caused by...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/8439791 |
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| _version_ | 1850175087139880960 |
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| author | Yohei Kubota Toh Yoon Ezekiel Wong |
| author_facet | Yohei Kubota Toh Yoon Ezekiel Wong |
| author_sort | Yohei Kubota |
| collection | DOAJ |
| description | When elderly patients are prescribed many different medications, the risk for developing serious adverse events should be kept in mind. One of these adverse events is agranulocytosis, which, although rare, can be life-threatening if left untreated. The majority of agranulocytosis cases are caused by drugs, including antibiotics. Here, we report a case of severe agranulocytosis in a 96-year-old woman following antibiotic therapy which was successfully managed using recombinant human granulocyte colony-stimulating factor (rhG-CSF) and the appropriate choice of antibiotics to treat her concomitant infection. |
| format | Article |
| id | doaj-art-d57ded2ea36a46c387586a20ee7cfe04 |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-d57ded2ea36a46c387586a20ee7cfe042025-08-20T02:19:31ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/84397918439791Severe Drug-Induced Agranulocytosis Successfully Treated with Recombinant Human Granulocyte Colony-Stimulating FactorYohei Kubota0Toh Yoon Ezekiel Wong1Department of Internal Medicine, Hiroshima Kyoritsu Hospital, Hiroshima, JapanDepartment of Internal Medicine, Hiroshima Kyoritsu Hospital, Hiroshima, JapanWhen elderly patients are prescribed many different medications, the risk for developing serious adverse events should be kept in mind. One of these adverse events is agranulocytosis, which, although rare, can be life-threatening if left untreated. The majority of agranulocytosis cases are caused by drugs, including antibiotics. Here, we report a case of severe agranulocytosis in a 96-year-old woman following antibiotic therapy which was successfully managed using recombinant human granulocyte colony-stimulating factor (rhG-CSF) and the appropriate choice of antibiotics to treat her concomitant infection.http://dx.doi.org/10.1155/2018/8439791 |
| spellingShingle | Yohei Kubota Toh Yoon Ezekiel Wong Severe Drug-Induced Agranulocytosis Successfully Treated with Recombinant Human Granulocyte Colony-Stimulating Factor Case Reports in Medicine |
| title | Severe Drug-Induced Agranulocytosis Successfully Treated with Recombinant Human Granulocyte Colony-Stimulating Factor |
| title_full | Severe Drug-Induced Agranulocytosis Successfully Treated with Recombinant Human Granulocyte Colony-Stimulating Factor |
| title_fullStr | Severe Drug-Induced Agranulocytosis Successfully Treated with Recombinant Human Granulocyte Colony-Stimulating Factor |
| title_full_unstemmed | Severe Drug-Induced Agranulocytosis Successfully Treated with Recombinant Human Granulocyte Colony-Stimulating Factor |
| title_short | Severe Drug-Induced Agranulocytosis Successfully Treated with Recombinant Human Granulocyte Colony-Stimulating Factor |
| title_sort | severe drug induced agranulocytosis successfully treated with recombinant human granulocyte colony stimulating factor |
| url | http://dx.doi.org/10.1155/2018/8439791 |
| work_keys_str_mv | AT yoheikubota severedruginducedagranulocytosissuccessfullytreatedwithrecombinanthumangranulocytecolonystimulatingfactor AT tohyoonezekielwong severedruginducedagranulocytosissuccessfullytreatedwithrecombinanthumangranulocytecolonystimulatingfactor |