Angiogenesis in Inflammatory Bowel Disease
Angiogenesis is an important component of pathogenesis of inflammatory bowel disease (IBD). Chronic inflammation and angiogenesis are two closely related processes. Chronic intestinal inflammation is dependent on angiogenesis and this angiogenesis is modulated by immune system in IBD. Angiogenesis i...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | International Journal of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2015/970890 |
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| _version_ | 1849695458544320512 |
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| author | Canan Alkim Huseyin Alkim Ali Riza Koksal Salih Boga Ilker Sen |
| author_facet | Canan Alkim Huseyin Alkim Ali Riza Koksal Salih Boga Ilker Sen |
| author_sort | Canan Alkim |
| collection | DOAJ |
| description | Angiogenesis is an important component of pathogenesis of inflammatory bowel disease (IBD). Chronic inflammation and angiogenesis are two closely related processes. Chronic intestinal inflammation is dependent on angiogenesis and this angiogenesis is modulated by immune system in IBD. Angiogenesis is a very complex process which includes multiple cell types, growth factors, cytokines, adhesion molecules, and signal transduction. Lymphangiogenesis is a new research area in the pathogenesis of IBD. While angiogenesis supports inflammation via leukocyte migration, carrying oxygen and nutrients, on the other hand, it has a major role in wound healing. Angiogenic molecules look like perfect targets for the treatment of IBD, but they have risk for serious side effects because of their nature. |
| format | Article |
| id | doaj-art-d577e8e121b3474c94d61b98c848d6bf |
| institution | DOAJ |
| issn | 2090-8040 2042-0099 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Inflammation |
| spelling | doaj-art-d577e8e121b3474c94d61b98c848d6bf2025-08-20T03:19:47ZengWileyInternational Journal of Inflammation2090-80402042-00992015-01-01201510.1155/2015/970890970890Angiogenesis in Inflammatory Bowel DiseaseCanan Alkim0Huseyin Alkim1Ali Riza Koksal2Salih Boga3Ilker Sen4Department of Gastroenterology, Şişli Hamidiye Etfal Training and Research Hospital, Şişli, 34360 Istanbul, TurkeyDepartment of Gastroenterology, Şişli Hamidiye Etfal Training and Research Hospital, Şişli, 34360 Istanbul, TurkeyDepartment of Gastroenterology, Şişli Hamidiye Etfal Training and Research Hospital, Şişli, 34360 Istanbul, TurkeyDepartment of Gastroenterology, Şişli Hamidiye Etfal Training and Research Hospital, Şişli, 34360 Istanbul, TurkeyDepartment of Gastroenterology, Şişli Hamidiye Etfal Training and Research Hospital, Şişli, 34360 Istanbul, TurkeyAngiogenesis is an important component of pathogenesis of inflammatory bowel disease (IBD). Chronic inflammation and angiogenesis are two closely related processes. Chronic intestinal inflammation is dependent on angiogenesis and this angiogenesis is modulated by immune system in IBD. Angiogenesis is a very complex process which includes multiple cell types, growth factors, cytokines, adhesion molecules, and signal transduction. Lymphangiogenesis is a new research area in the pathogenesis of IBD. While angiogenesis supports inflammation via leukocyte migration, carrying oxygen and nutrients, on the other hand, it has a major role in wound healing. Angiogenic molecules look like perfect targets for the treatment of IBD, but they have risk for serious side effects because of their nature.http://dx.doi.org/10.1155/2015/970890 |
| spellingShingle | Canan Alkim Huseyin Alkim Ali Riza Koksal Salih Boga Ilker Sen Angiogenesis in Inflammatory Bowel Disease International Journal of Inflammation |
| title | Angiogenesis in Inflammatory Bowel Disease |
| title_full | Angiogenesis in Inflammatory Bowel Disease |
| title_fullStr | Angiogenesis in Inflammatory Bowel Disease |
| title_full_unstemmed | Angiogenesis in Inflammatory Bowel Disease |
| title_short | Angiogenesis in Inflammatory Bowel Disease |
| title_sort | angiogenesis in inflammatory bowel disease |
| url | http://dx.doi.org/10.1155/2015/970890 |
| work_keys_str_mv | AT cananalkim angiogenesisininflammatoryboweldisease AT huseyinalkim angiogenesisininflammatoryboweldisease AT alirizakoksal angiogenesisininflammatoryboweldisease AT salihboga angiogenesisininflammatoryboweldisease AT ilkersen angiogenesisininflammatoryboweldisease |