Novel anti-microbial peptide SR-0379 accelerates wound healing via the PI3 kinase/Akt/mTOR pathway.

Novel anti-microbial peptide SR-0379 accelerates wound healing via the PI3 kinase/Akt/mTOR pathway.

We developed a novel cationic antimicrobial peptide, AG30/5C, which demonstrates angiogenic properties similar to those of LL-37 or PR39. However, improvement of its stability and cost efficacy are required for clinical application. Therefore, we examined the metabolites of AG30/5C, which provided t...

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Bibliographic Details
Main Authors: Hideki Tomioka, Hironori Nakagami, Akiko Tenma, Yoshimi Saito, Toshihiro Kaga, Toshihide Kanamori, Nao Tamura, Kazunori Tomono, Yasufumi Kaneda, Ryuichi Morishita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0092597&type=printable
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