CLINICAL MANIFESTATIONS OF IMMUNOPATHOLOGY AS A RISK FACTOR OF TUBERCULOSIS IN CHILDREN INCASE OF THE SINGLE INFECTION AND CONCURRENT HIV INFECTION
In order to detect tuberculosis risk factors among clinical manifestations of immunopathology, a retrospective study was conducted among 177 children (55 children with tuberculous infection only, 50 children with concurrent HIV, and 72 healthy children). The predictive significance of infectious imm...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2017-12-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1066 |
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| author | S. N. Shugаevа A. G. Petrovа |
| author_facet | S. N. Shugаevа A. G. Petrovа |
| author_sort | S. N. Shugаevа |
| collection | DOAJ |
| description | In order to detect tuberculosis risk factors among clinical manifestations of immunopathology, a retrospective study was conducted among 177 children (55 children with tuberculous infection only, 50 children with concurrent HIV, and 72 healthy children). The predictive significance of infectious immunopathology syndrome was identified, this syndrome was registered in the major part of children infected with tuberculous infection (40%, OR=6.3) and in all children with TB/HIV co-infection. The following risk factors of developing active disease in case of tuberculous infection were identified: recurrent pneumonias (20%, OR=17.8) and relapsing bronchitis (38.3%, OR=6.8). And the history of clinical manifestations of infectious, lymphoproliferative and autoimmune immunopathology syndromes in the children ill with tuberculosis can be the indirect evidence of concurrent HIV infection. |
| format | Article |
| id | doaj-art-d571858bea6042f09cc87cc4decc552b |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2017-12-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-d571858bea6042f09cc87cc4decc552b2025-08-20T01:47:52ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062017-12-019511697310.21292/2075-1230-2017-95-11-69-721066CLINICAL MANIFESTATIONS OF IMMUNOPATHOLOGY AS A RISK FACTOR OF TUBERCULOSIS IN CHILDREN INCASE OF THE SINGLE INFECTION AND CONCURRENT HIV INFECTIONS. N. Shugаevа0A. G. Petrovа1Irkutsk State Medical Academy of Postgraduate Education, Branch of Russian Medical Academy of On-going Professional EducationIrkutsk State Medical UniversityIn order to detect tuberculosis risk factors among clinical manifestations of immunopathology, a retrospective study was conducted among 177 children (55 children with tuberculous infection only, 50 children with concurrent HIV, and 72 healthy children). The predictive significance of infectious immunopathology syndrome was identified, this syndrome was registered in the major part of children infected with tuberculous infection (40%, OR=6.3) and in all children with TB/HIV co-infection. The following risk factors of developing active disease in case of tuberculous infection were identified: recurrent pneumonias (20%, OR=17.8) and relapsing bronchitis (38.3%, OR=6.8). And the history of clinical manifestations of infectious, lymphoproliferative and autoimmune immunopathology syndromes in the children ill with tuberculosis can be the indirect evidence of concurrent HIV infection.https://www.tibl-journal.com/jour/article/view/1066tuberculosishiv infectionrisk factorimmune pathologyinfectious immunopathological syndromechildren |
| spellingShingle | S. N. Shugаevа A. G. Petrovа CLINICAL MANIFESTATIONS OF IMMUNOPATHOLOGY AS A RISK FACTOR OF TUBERCULOSIS IN CHILDREN INCASE OF THE SINGLE INFECTION AND CONCURRENT HIV INFECTION Туберкулез и болезни лёгких tuberculosis hiv infection risk factor immune pathology infectious immunopathological syndrome children |
| title | CLINICAL MANIFESTATIONS OF IMMUNOPATHOLOGY AS A RISK FACTOR OF TUBERCULOSIS IN CHILDREN INCASE OF THE SINGLE INFECTION AND CONCURRENT HIV INFECTION |
| title_full | CLINICAL MANIFESTATIONS OF IMMUNOPATHOLOGY AS A RISK FACTOR OF TUBERCULOSIS IN CHILDREN INCASE OF THE SINGLE INFECTION AND CONCURRENT HIV INFECTION |
| title_fullStr | CLINICAL MANIFESTATIONS OF IMMUNOPATHOLOGY AS A RISK FACTOR OF TUBERCULOSIS IN CHILDREN INCASE OF THE SINGLE INFECTION AND CONCURRENT HIV INFECTION |
| title_full_unstemmed | CLINICAL MANIFESTATIONS OF IMMUNOPATHOLOGY AS A RISK FACTOR OF TUBERCULOSIS IN CHILDREN INCASE OF THE SINGLE INFECTION AND CONCURRENT HIV INFECTION |
| title_short | CLINICAL MANIFESTATIONS OF IMMUNOPATHOLOGY AS A RISK FACTOR OF TUBERCULOSIS IN CHILDREN INCASE OF THE SINGLE INFECTION AND CONCURRENT HIV INFECTION |
| title_sort | clinical manifestations of immunopathology as a risk factor of tuberculosis in children incase of the single infection and concurrent hiv infection |
| topic | tuberculosis hiv infection risk factor immune pathology infectious immunopathological syndrome children |
| url | https://www.tibl-journal.com/jour/article/view/1066 |
| work_keys_str_mv | AT snshugaeva clinicalmanifestationsofimmunopathologyasariskfactoroftuberculosisinchildrenincaseofthesingleinfectionandconcurrenthivinfection AT agpetrova clinicalmanifestationsofimmunopathologyasariskfactoroftuberculosisinchildrenincaseofthesingleinfectionandconcurrenthivinfection |