Postural Orthostatic Tachycardia Syndrome (POTS) – A Review of Pathophysiological Mechanisms, Diagnosis and Therapy
Introduction Postural Orthostatic Tachycardia Syndrome (POTS) is a chronic disorder of the autonomic nervous system. It is characterized by orthostatic tachycardia and orthostatic intolerance upon standing, without low blood pressure. It affects multiple body systems, leading to a wide range of sy...
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Kazimierz Wielki University
2024-11-01
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| Series: | Journal of Education, Health and Sport |
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| Online Access: | https://apcz.umk.pl/JEHS/article/view/56193 |
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| author | Alicja Dziedzic Daria Furtak Wiktor Grela Jagoda Niewiadomska Paulina Głogowska Dawid Tulej Dominika Marciniuk Natalia Gniaź Aleksandra Górska Natalia Marko |
| author_facet | Alicja Dziedzic Daria Furtak Wiktor Grela Jagoda Niewiadomska Paulina Głogowska Dawid Tulej Dominika Marciniuk Natalia Gniaź Aleksandra Górska Natalia Marko |
| author_sort | Alicja Dziedzic |
| collection | DOAJ |
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Introduction
Postural Orthostatic Tachycardia Syndrome (POTS) is a chronic disorder of the autonomic nervous system. It is characterized by orthostatic tachycardia and orthostatic intolerance upon standing, without low blood pressure. It affects multiple body systems, leading to a wide range of symptoms that contribute to debilitation and reduced functionality. The disorder has significant functional and economic consequences, although its underlying mechanisms remain only partially understood. Many POTS patients receive inadequate care due to limited understanding of the etiology of POTS, a lack of evidence-based treatment options, and minimal training among physicians in recognizing and managing POTS.
Aim of the study
The purpose of this review is to provide a comprehensive overview of POTS, including its etiology, associated comorbidities, diagnostic challenges, and approaches to diagnosis, as well as potential pharmacological and non-pharmacological treatment options.
Material and Method
The literature search methodology involved using the keyword "POTS" in combination with terms such as "etiology," "treatment," "diagnosis," "symptoms," "long COVID-19," and "exercise." Searches were conducted in the PubMed and Google Scholar databases, focusing primarily on review articles and clinical trials.
Conclusions
Raising awareness of POTS among physicians is essential for delivering optimal healthcare to patients. Despite the prevalence of POTS and its significant impact on patients' lives, research funding remains disproportionately low. Strengthening research infrastructure is crucial to understand the pathophysiology of POTS and to standardize evaluation tools, outcome measures, and patient care.
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| format | Article |
| id | doaj-art-d56426ecbb6a4e70907f43ca387a60ff |
| institution | OA Journals |
| issn | 2391-8306 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj-art-d56426ecbb6a4e70907f43ca387a60ff2025-08-20T02:23:11ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062024-11-017110.12775/JEHS.2024.71.56193Postural Orthostatic Tachycardia Syndrome (POTS) – A Review of Pathophysiological Mechanisms, Diagnosis and TherapyAlicja Dziedzic0Daria Furtak1Wiktor Grela2Jagoda Niewiadomska3Paulina Głogowska4Dawid Tulej5Dominika Marciniuk6Natalia Gniaź7Aleksandra Górska8Natalia Marko9Uniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w Lublinie Introduction Postural Orthostatic Tachycardia Syndrome (POTS) is a chronic disorder of the autonomic nervous system. It is characterized by orthostatic tachycardia and orthostatic intolerance upon standing, without low blood pressure. It affects multiple body systems, leading to a wide range of symptoms that contribute to debilitation and reduced functionality. The disorder has significant functional and economic consequences, although its underlying mechanisms remain only partially understood. Many POTS patients receive inadequate care due to limited understanding of the etiology of POTS, a lack of evidence-based treatment options, and minimal training among physicians in recognizing and managing POTS. Aim of the study The purpose of this review is to provide a comprehensive overview of POTS, including its etiology, associated comorbidities, diagnostic challenges, and approaches to diagnosis, as well as potential pharmacological and non-pharmacological treatment options. Material and Method The literature search methodology involved using the keyword "POTS" in combination with terms such as "etiology," "treatment," "diagnosis," "symptoms," "long COVID-19," and "exercise." Searches were conducted in the PubMed and Google Scholar databases, focusing primarily on review articles and clinical trials. Conclusions Raising awareness of POTS among physicians is essential for delivering optimal healthcare to patients. Despite the prevalence of POTS and its significant impact on patients' lives, research funding remains disproportionately low. Strengthening research infrastructure is crucial to understand the pathophysiology of POTS and to standardize evaluation tools, outcome measures, and patient care. https://apcz.umk.pl/JEHS/article/view/56193postural orthostatic tachycardia syndromePOTSdiagnosistreatmentpathophysiology |
| spellingShingle | Alicja Dziedzic Daria Furtak Wiktor Grela Jagoda Niewiadomska Paulina Głogowska Dawid Tulej Dominika Marciniuk Natalia Gniaź Aleksandra Górska Natalia Marko Postural Orthostatic Tachycardia Syndrome (POTS) – A Review of Pathophysiological Mechanisms, Diagnosis and Therapy Journal of Education, Health and Sport postural orthostatic tachycardia syndrome POTS diagnosis treatment pathophysiology |
| title | Postural Orthostatic Tachycardia Syndrome (POTS) – A Review of Pathophysiological Mechanisms, Diagnosis and Therapy |
| title_full | Postural Orthostatic Tachycardia Syndrome (POTS) – A Review of Pathophysiological Mechanisms, Diagnosis and Therapy |
| title_fullStr | Postural Orthostatic Tachycardia Syndrome (POTS) – A Review of Pathophysiological Mechanisms, Diagnosis and Therapy |
| title_full_unstemmed | Postural Orthostatic Tachycardia Syndrome (POTS) – A Review of Pathophysiological Mechanisms, Diagnosis and Therapy |
| title_short | Postural Orthostatic Tachycardia Syndrome (POTS) – A Review of Pathophysiological Mechanisms, Diagnosis and Therapy |
| title_sort | postural orthostatic tachycardia syndrome pots a review of pathophysiological mechanisms diagnosis and therapy |
| topic | postural orthostatic tachycardia syndrome POTS diagnosis treatment pathophysiology |
| url | https://apcz.umk.pl/JEHS/article/view/56193 |
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