Matrix-bound EGF promotes malignant phenotypes of breast cancer organoids in the biomimetic ECM of alginate

As multiple malignant phenotypes appear during cancer progression, it is essential to recognize the possible mechanisms from original to metastatic states. However, both two-dimensional monolayer cell culture and in vivo animal models have their inherent limitations, such as lack of proper cell-ECM...

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Bibliographic Details
Main Authors: Xue-Yu Chen, Meng-Yuan Wang, Xin Shu, Jun Li, Ruizhi Tang, Xi-Qiu Liu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425003783
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