Adherence to Antidiabetic Medications among Women with Gestational Diabetes
Background. Optimal adherence to prescribed medications in women with gestational diabetes is relevant for perinatal outcomes. Objective. To summarize available information on the prevalence and factors contributing to medication adherence in women with gestational diabetes from the biological and p...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2021/9941538 |
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| author | Michelle Asiedu-Danso Irene A. Kretchy Jeremiah Kobby Sekyi Augustina Koduah |
| author_facet | Michelle Asiedu-Danso Irene A. Kretchy Jeremiah Kobby Sekyi Augustina Koduah |
| author_sort | Michelle Asiedu-Danso |
| collection | DOAJ |
| description | Background. Optimal adherence to prescribed medications in women with gestational diabetes is relevant for perinatal outcomes. Objective. To summarize available information on the prevalence and factors contributing to medication adherence in women with gestational diabetes from the biological and psychosocial perspectives. Methods. A literature search on adherence in gestational diabetes was conducted in PubMed/MEDLINE, CINAHL, Scopus, and the Directory of Open Access Journals for studies published on the topic. The Arksey and O’Malley framework for scoping reviews was used to explore and summarize the evidence. Results. A total of 2395 studies were retrieved of which 13 fully met the eligibility criteria. The studies were reported in Zimbabwe (n=5), Iran (n=1), Mexico (n=1), South India (n=1), the United States of America (n=4), and one multinational study covering Australia, Europe, North and South America. The main types of antidiabetic medications used were insulin (n=6), metformin (n=4), and glyburide (n=2). The prevalence of adherence ranged from 35.6% to 97%, with the assessment tool being self-report measures (n=8). The main factors associated with nonadherence included worsening pregnancy symptoms, side effects of medications, perceived risks, mental health symptoms, poor social support, and socioeconomic status. Recommendations that evolved from the studies to improve adherence included education, counselling, improved support networks, and social interventions, while the main reported interventional study employed continuous education on the impact of adherence on perinatal outcomes. Conclusion. Medication nonadherence in gestational diabetes seems to be influenced by multiple factors with some educational interventions positively impacting adherence behaviours. Thus, future research in women with gestational diabetes could consider interventions from a multifactorial perspective to improve therapeutic outcomes. |
| format | Article |
| id | doaj-art-d552e8561706468993da31036a67348f |
| institution | DOAJ |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-d552e8561706468993da31036a67348f2025-08-20T03:23:38ZengWileyJournal of Diabetes Research2314-67452314-67532021-01-01202110.1155/2021/99415389941538Adherence to Antidiabetic Medications among Women with Gestational DiabetesMichelle Asiedu-Danso0Irene A. Kretchy1Jeremiah Kobby Sekyi2Augustina Koduah3Department of Pharmacy Practice and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, University of Ghana, P. O. Box LG, 43 Legon, GhanaDepartment of Pharmacy Practice and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, University of Ghana, P. O. Box LG, 43 Legon, GhanaDepartment of Pharmacy Practice and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, University of Ghana, P. O. Box LG, 43 Legon, GhanaDepartment of Pharmacy Practice and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, University of Ghana, P. O. Box LG, 43 Legon, GhanaBackground. Optimal adherence to prescribed medications in women with gestational diabetes is relevant for perinatal outcomes. Objective. To summarize available information on the prevalence and factors contributing to medication adherence in women with gestational diabetes from the biological and psychosocial perspectives. Methods. A literature search on adherence in gestational diabetes was conducted in PubMed/MEDLINE, CINAHL, Scopus, and the Directory of Open Access Journals for studies published on the topic. The Arksey and O’Malley framework for scoping reviews was used to explore and summarize the evidence. Results. A total of 2395 studies were retrieved of which 13 fully met the eligibility criteria. The studies were reported in Zimbabwe (n=5), Iran (n=1), Mexico (n=1), South India (n=1), the United States of America (n=4), and one multinational study covering Australia, Europe, North and South America. The main types of antidiabetic medications used were insulin (n=6), metformin (n=4), and glyburide (n=2). The prevalence of adherence ranged from 35.6% to 97%, with the assessment tool being self-report measures (n=8). The main factors associated with nonadherence included worsening pregnancy symptoms, side effects of medications, perceived risks, mental health symptoms, poor social support, and socioeconomic status. Recommendations that evolved from the studies to improve adherence included education, counselling, improved support networks, and social interventions, while the main reported interventional study employed continuous education on the impact of adherence on perinatal outcomes. Conclusion. Medication nonadherence in gestational diabetes seems to be influenced by multiple factors with some educational interventions positively impacting adherence behaviours. Thus, future research in women with gestational diabetes could consider interventions from a multifactorial perspective to improve therapeutic outcomes.http://dx.doi.org/10.1155/2021/9941538 |
| spellingShingle | Michelle Asiedu-Danso Irene A. Kretchy Jeremiah Kobby Sekyi Augustina Koduah Adherence to Antidiabetic Medications among Women with Gestational Diabetes Journal of Diabetes Research |
| title | Adherence to Antidiabetic Medications among Women with Gestational Diabetes |
| title_full | Adherence to Antidiabetic Medications among Women with Gestational Diabetes |
| title_fullStr | Adherence to Antidiabetic Medications among Women with Gestational Diabetes |
| title_full_unstemmed | Adherence to Antidiabetic Medications among Women with Gestational Diabetes |
| title_short | Adherence to Antidiabetic Medications among Women with Gestational Diabetes |
| title_sort | adherence to antidiabetic medications among women with gestational diabetes |
| url | http://dx.doi.org/10.1155/2021/9941538 |
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