Role of fluorodeoxyglucose-positron emission tomography/computed tomography in the evaluation of head and neck carcinoma

Fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET-CT) has been playing a pivotal role in tumor imaging for the past 20 years. Head and neck (HN) cancers are a good example that can illustrate such unique role of FDG imaging contributing to the patient's management....

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Main Authors: Moheieldin Abouzied, Ahmed Fathala, Abdulaziz Alsugair, Ahmad Al Muhaideb, Mohammed Al Qahtani
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2017-10-01
Series:World Journal of Nuclear Medicine
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_40_17
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author Moheieldin Abouzied
Ahmed Fathala
Abdulaziz Alsugair
Ahmad Al Muhaideb
Mohammed Al Qahtani
author_facet Moheieldin Abouzied
Ahmed Fathala
Abdulaziz Alsugair
Ahmad Al Muhaideb
Mohammed Al Qahtani
author_sort Moheieldin Abouzied
collection DOAJ
description Fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET-CT) has been playing a pivotal role in tumor imaging for the past 20 years. Head and neck (HN) cancers are a good example that can illustrate such unique role of FDG imaging contributing to the patient's management. In this review article, we will describe the normal physiological distribution of FDG within HN structures focusing on its limitations and pitfalls. In addition, we will be also describing its role in the initial staging and restaging of the disease, particularly with regard to therapy response assessment. Furthermore, its role in the evaluation of patients with malignant cervical adenopathy from an unknown primary will be described. In 2016, the Royal College of Radiologists in its third edition published evidence-based guidelines for PET-CT use in HN cancer emphasizing its rule in all these clinical scenarios that are being described in this review. Finally, we will be highlighting future directions in the field of molecular imaging of HN tumors with a special emphasis on the new PET tracers.
format Article
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institution Kabale University
issn 1450-1147
1607-3312
language English
publishDate 2017-10-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series World Journal of Nuclear Medicine
spelling doaj-art-d547ab357ab54aeb9c8dfd1af9202df92025-08-20T03:48:36ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122017-10-01160425726510.4103/wjnm.WJNM_40_17Role of fluorodeoxyglucose-positron emission tomography/computed tomography in the evaluation of head and neck carcinomaMoheieldin Abouzied0Ahmed Fathala1Abdulaziz Alsugair2Ahmad Al Muhaideb3Mohammed Al Qahtani4Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi ArabiaDepartment of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi ArabiaDepartment of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi ArabiaDepartment of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi ArabiaDepartment of Cyclotron and Radiopharmaceuticals, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi ArabiaFluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET-CT) has been playing a pivotal role in tumor imaging for the past 20 years. Head and neck (HN) cancers are a good example that can illustrate such unique role of FDG imaging contributing to the patient's management. In this review article, we will describe the normal physiological distribution of FDG within HN structures focusing on its limitations and pitfalls. In addition, we will be also describing its role in the initial staging and restaging of the disease, particularly with regard to therapy response assessment. Furthermore, its role in the evaluation of patients with malignant cervical adenopathy from an unknown primary will be described. In 2016, the Royal College of Radiologists in its third edition published evidence-based guidelines for PET-CT use in HN cancer emphasizing its rule in all these clinical scenarios that are being described in this review. Finally, we will be highlighting future directions in the field of molecular imaging of HN tumors with a special emphasis on the new PET tracers.http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_40_17assessment of response to therapyfluorodeoxyglucose-positron emission tomography/computed tomographyhead and neck cancerinitial stagingrestaging
spellingShingle Moheieldin Abouzied
Ahmed Fathala
Abdulaziz Alsugair
Ahmad Al Muhaideb
Mohammed Al Qahtani
Role of fluorodeoxyglucose-positron emission tomography/computed tomography in the evaluation of head and neck carcinoma
World Journal of Nuclear Medicine
assessment of response to therapy
fluorodeoxyglucose-positron emission tomography/computed tomography
head and neck cancer
initial staging
restaging
title Role of fluorodeoxyglucose-positron emission tomography/computed tomography in the evaluation of head and neck carcinoma
title_full Role of fluorodeoxyglucose-positron emission tomography/computed tomography in the evaluation of head and neck carcinoma
title_fullStr Role of fluorodeoxyglucose-positron emission tomography/computed tomography in the evaluation of head and neck carcinoma
title_full_unstemmed Role of fluorodeoxyglucose-positron emission tomography/computed tomography in the evaluation of head and neck carcinoma
title_short Role of fluorodeoxyglucose-positron emission tomography/computed tomography in the evaluation of head and neck carcinoma
title_sort role of fluorodeoxyglucose positron emission tomography computed tomography in the evaluation of head and neck carcinoma
topic assessment of response to therapy
fluorodeoxyglucose-positron emission tomography/computed tomography
head and neck cancer
initial staging
restaging
url http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_40_17
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